| The Structural Connectivity Pattern of the Default Mode Network and Its Association with Memory and Anxiety | |
Tao, Yan1,2 ; Liu, Bing1,2; Zhang, Xiaolong1,2; Li, Jin1,2; Qin, Wen3; Yu, Chunshui3; Jiang, Tianzi1,2,4,5
| |
| 发表期刊 | FRONTIERS IN NEUROANATOMY
 |
| 2015-11-26 | |
| 卷号 | 9期号:无页码:152 |
| 文章类型 | Article |
| 摘要 | The default mode network (DMN) is one of the most widely studied resting state functional networks. The structural basis for the DMN is of particular interest and has been studied by several researchers using diffusion tensor imaging (DTI). Most of these previous studies focused on a few regions or white matter tracts of the DMN so that the global structural connectivity pattern and network properties of the DMN remain unclear. Moreover, evidences indicate that the DMN is involved in both memory and emotion, but how the DMN regulates memory and anxiety from the perspective of the whole DMN structural network remains unknown. We used multimodal neuroimaging methods to investigate the structural connectivity pattern of the DMN and the association of its network properties with memory and anxiety in 205 young healthy subjects with age ranging from 18 to 29 years old. The Group ICA method was used to extract the DMN component from functional magnetic resonance imaging (fMRI) data and a probabilistic fiber tractography technique based on DTI data was applied to construct the global structural connectivity pattern of the DMN. Then we used the graph theory method to analyze the DMN structural network and found that memory quotient (MQ) score was significantly positively correlated with the global and local efficiency of the DMN whereas anxiety was found to be negatively correlated with the efficiency. The strong structural connectivity between multiple brain regions within DMN may reflect that the DMN has certain structural basis. Meanwhile, the results we found that the network efficiency of the DMN were related to memory and anxiety measures, indicated that the DMN may play a role in the memory and anxiety. |
| 关键词 | Dti Default Mode Network Memory Anxiety Structural Network |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.3389/fnana.2015.00152 |
| 关键词[WOS] | MEDIAL PREFRONTAL CORTEX ; STATE FUNCTIONAL CONNECTIVITY ; POSTERIOR CINGULATE CORTEX ; MILD COGNITIVE IMPAIRMENT ; RESTING-STATE ; BIPOLAR DISORDER ; ALZHEIMERS-DISEASE ; VENTRAL HIPPOCAMPUS ; BRAIN-FUNCTION ; SCHIZOPHRENIA |
| 收录类别 | SCI |
| 语种 | 英语 |
| 项目资助者 | National Key Basic Research and Development Program (973)(2011CB707800) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB02030300) ; Natural Science Foundation of China(91232718 ; Youth Innovation Promotion Association, Chinese Academy of Science ; 91132301) |
| WOS研究方向 | Anatomy & Morphology ; Neurosciences & Neurology |
| WOS类目 | Anatomy & Morphology ; Neurosciences |
| WOS记录号 | WOS:000365850800001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ia.ac.cn/handle/173211/10532 |
| 专题 | 脑图谱与类脑智能实验室_脑网络组研究 |
| 通讯作者 | Liu, Bing |
| 作者单位 | 1.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 2.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing, Peoples R China 3.Tianjin Med Univ, Dept Radiol, Gen Hosp, Tianjin, Peoples R China 4.Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia 5.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab Neuroinformat, Chengdu 610054, Peoples R China |
| 第一作者单位 | 模式识别国家重点实验室 |
| 通讯作者单位 | 模式识别国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Tao, Yan,Liu, Bing,Zhang, Xiaolong,et al. The Structural Connectivity Pattern of the Default Mode Network and Its Association with Memory and Anxiety[J]. FRONTIERS IN NEUROANATOMY,2015,9(无):152. |
| APA | Tao, Yan.,Liu, Bing.,Zhang, Xiaolong.,Li, Jin.,Qin, Wen.,...&Jiang, Tianzi.(2015).The Structural Connectivity Pattern of the Default Mode Network and Its Association with Memory and Anxiety.FRONTIERS IN NEUROANATOMY,9(无),152. |
| MLA | Tao, Yan,et al."The Structural Connectivity Pattern of the Default Mode Network and Its Association with Memory and Anxiety".FRONTIERS IN NEUROANATOMY 9.无(2015):152. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| The Structural Conne（1735KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论