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Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis
Wu, Min1; Lu, Peng4; Shi, Luwen1; Li, Shao2,3
2015-11-10
发表期刊ONCOTARGET
卷号6期号:35页码:38283-38295
文章类型Article
摘要Based on the nationwide survey into inpatients' utilization of the health service covered by China's urban basic medical insurance from 2008 to 2010, we analyzed the use rate, cancer profile and combined use of anticancer Chinese patent medicines (CPMs) on 51,382 insured cancer patients by using statistical, bi-clustering and network methods. We found that 42.4% of 51,382 cancer patients used 33 anticancer CPMs, and 51.7% used 71 anticancer Western medicines (WMs). The CPMs were most often used in lung (52%) and nasopharynx (52%) cancer patients, and least in bladder cancer (21%) and leukemia of unspecified cell type (21%) patients. The cost per patient for all 33 anticancer CPMs was 2069RMB, lower than that of the WMs (3458RMB). The cancer profile of commonly used CPMs and WMs for the top 17 cancers (>500 sampled patients) were provided, indicating anticancer CPMs had a broad spectrum of cancers and lacked selectivity in cancer treatment (CPM mean CV = 49%; WM mean CV = 152%). Moreover, 24.8% of the cancer patients used both CPMs and WMs, and CPM-WM combined use networks were constructed for four major cancers. This first nationwide analysis revealed the use characteristics and herb-drug combined use patterns of insurance covered anticancer CPMs in China. The study offers valuable information to guide future studies of the precision, safety and standard use of CPMs.
关键词Traditional Chinese Medicine Cancer Treatment Medical Insurance Nationwide Survey Herb-drug Network
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]HERBAL FORMULAS ; ASTRAGALI-RADIX ; MATRINE ; CELLS
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China(81225025 ; 91229201)
WOS研究方向Oncology ; Cell Biology
WOS类目Oncology ; Cell Biology
WOS记录号WOS:000366113200096
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/10642
专题综合信息系统研究中心
作者单位1.Peking Univ, Sch Pharmaceut Sci, Dept Pharm Adm & Clin Pharm, Beijing 100871, Peoples R China
2.Tsinghua Univ, Dept Automat, TNLIST, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China
3.Tsinghua Univ, Dept Automat, TNLIST, Bioinformat Div, Beijing 100084, Peoples R China
4.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
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GB/T 7714
Wu, Min,Lu, Peng,Shi, Luwen,et al. Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis[J]. ONCOTARGET,2015,6(35):38283-38295.
APA Wu, Min,Lu, Peng,Shi, Luwen,&Li, Shao.(2015).Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis.ONCOTARGET,6(35),38283-38295.
MLA Wu, Min,et al."Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis".ONCOTARGET 6.35(2015):38283-38295.
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