Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
Hybrid simplified spherical harmonics with diffusion equation for light propagation in tissues | |
Chen, Xueli1,2; Sun, Fangfang1,2; Yang, Defu1,2; Ren, Shenghan1,2; Zhang, Qian3; Liang, Jimin1,2 | |
发表期刊 | PHYSICS IN MEDICINE AND BIOLOGY |
2015-08-21 | |
卷号 | 60期号:16页码:6305-6322 |
文章类型 | Article |
摘要 | Aiming at the limitations of the simplified spherical harmonics approximation (SPN) and diffusion equation (DE) in describing the light propagation in tissues, a hybrid simplified spherical harmonics with diffusion equation (HSDE) based diffuse light transport model is proposed. In the HSDE model, the living body is first segmented into several major organs, and then the organs are divided into high scattering tissues and other tissues. DE and SPN are employed to describe the light propagation in these two kinds of tissues respectively, which are finally coupled using the established boundary coupling condition. The HSDE model makes full use of the advantages of SPN and DE, and abandons their disadvantages, so that it can provide a perfect balance between accuracy and computation time. Using the finite element method, the HSDE is solved for light flux density map on body surface. The accuracy and efficiency of the HSDE are validated with both regular geometries and digital mouse model based simulations. Corresponding results reveal that a comparable accuracy and much less computation time are achieved compared with the SPN model as well as a much better accuracy compared with the DE one. |
关键词 | Hybrid Light Transport Model Spn De Hsde Fluorescence/bioluminescence Tomography |
WOS标题词 | Science & Technology ; Technology ; Life Sciences & Biomedicine |
DOI | 10.1088/0031-9155/60/16/6305 |
关键词[WOS] | FLUORESCENCE MOLECULAR TOMOGRAPHY ; RADIATIVE-TRANSFER EQUATION ; NON-SCATTERING REGIONS ; BIOLUMINESCENCE TOMOGRAPHY ; OPTICAL TOMOGRAPHY ; IN-VIVO ; IMAGE-RECONSTRUCTION ; PHOTON MIGRATION ; TURBID MEDIA ; APPROXIMATION |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Engineering ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Engineering, Biomedical ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000361052600011 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/10741 |
专题 | 中国科学院分子影像重点实验室 |
作者单位 | 1.Xidian Univ, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China 2.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Xueli,Sun, Fangfang,Yang, Defu,et al. Hybrid simplified spherical harmonics with diffusion equation for light propagation in tissues[J]. PHYSICS IN MEDICINE AND BIOLOGY,2015,60(16):6305-6322. |
APA | Chen, Xueli,Sun, Fangfang,Yang, Defu,Ren, Shenghan,Zhang, Qian,&Liang, Jimin.(2015).Hybrid simplified spherical harmonics with diffusion equation for light propagation in tissues.PHYSICS IN MEDICINE AND BIOLOGY,60(16),6305-6322. |
MLA | Chen, Xueli,et al."Hybrid simplified spherical harmonics with diffusion equation for light propagation in tissues".PHYSICS IN MEDICINE AND BIOLOGY 60.16(2015):6305-6322. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
HSDE for light propa(1080KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
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