| Progressive Thinning of Visual Motion area in lower limb amputees | |
Jiang, Guangyao1; Li, Chuanming1; Wu, Jixiang2; Jiang, Tianzi3 ; Zhang, Yi4; Zhao, Lu5; Evans, Alan C.5; Li, Lei2; Ran, Shuhua1; Yin, Xuntao1,5; Wang, Jian1
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| 发表期刊 | FRONTIERS IN HUMAN NEUROSCIENCE
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| 2016-03-01 | |
| 卷号 | 10 |
| 文章类型 | Article |
| 摘要 | Accumulating evidence has indicated that amputation or deafferentation of a limb induces functional or structural reorganization in the visual areas. However, the extent of the visual areas involved after lower limb amputation remains uncertain. In this investigation, we studied 48 adult patients with unilateral lower limb amputation and 48 matched healthy controls using T1-weighted magnetic resonance imaging. Template-based regions of interest analysis was implemented to detect the changes of cortical thickness in the specific visual areas. Compared with normal controls, amputees exhibited significantly lower thickness in the V5/middle temporal (V5/MT+) visual area, as well as a trend of cortical thinning in the V3d. There was no significant difference in the other visual areas between the two groups. In addition, no significant difference of cortical thickness was found between patients with amputation at different levels. Across all amputees, correlation analyses revealed that the cortical thickness of the V5/MT+ was negatively correlated to the time since amputation. In conclusion, our findings indicate that the amputation of unilateral lower limb could induce changes in the motor-related visual cortex and provide an update on the plasticity of the human brain after limb injury. |
| WOS标题词 | Science & Technology ; Social Sciences ; Life Sciences & Biomedicine |
| DOI | 10.3389/fnhum.2016.00079 |
| 关键词[WOS] | MAGNETIC-RESONANCE IMAGES ; COORDINATE SYSTEM ; MATTER CHANGES ; HUMAN HOMOLOG ; MOTOR CORTEX ; PAIN ; AMPUTATION ; BRAIN ; REORGANIZATION ; STIMULATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| 项目资助者 | National Natural Science Foundation of China for Young Scholars(81301205) ; Open Project Program of the National Laboratory of Pattern Recognition (NLPR) in China(201306283) |
| WOS研究方向 | Neurosciences & Neurology ; Psychology |
| WOS类目 | Neurosciences ; Psychology |
| WOS记录号 | WOS:000371166100001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ia.ac.cn/handle/173211/11359 |
| 专题 | 脑图谱与类脑智能实验室_脑网络组研究 |
| 作者单位 | 1.Third Mil Med Univ, Southwest Hosp, Dept Radiol, Chongqing, Peoples R China 2.Third Mil Med Univ, Southwest Hosp, Dept Rehabil, Chongqing, Peoples R China 3.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China 4.Tradit Chinese Med Hosp Taiwan, Dept Osteol, Taipei, Taiwan 5.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ, Canada |
| 推荐引用方式 GB/T 7714 | Jiang, Guangyao,Li, Chuanming,Wu, Jixiang,et al. Progressive Thinning of Visual Motion area in lower limb amputees[J]. FRONTIERS IN HUMAN NEUROSCIENCE,2016,10. |
| APA | Jiang, Guangyao.,Li, Chuanming.,Wu, Jixiang.,Jiang, Tianzi.,Zhang, Yi.,...&Wang, Jian.(2016).Progressive Thinning of Visual Motion area in lower limb amputees.FRONTIERS IN HUMAN NEUROSCIENCE,10. |
| MLA | Jiang, Guangyao,et al."Progressive Thinning of Visual Motion area in lower limb amputees".FRONTIERS IN HUMAN NEUROSCIENCE 10(2016). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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