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Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction
Jiang, Shixin1; Liu, Jie1; An, Yu1; Zhang, Guanglei1; Ye, Jinzuo2; Mao, Yamin2; He, Kunshan2; Chi, Chongwei2,3; Tian, Jie2,3
2016-06-01
发表期刊BIOMEDICAL OPTICS EXPRESS
卷号7期号:6页码:2342-2359
文章类型Article
摘要Fluorescence molecular tomography (FMT) is a promising tomographic method in preclinical research, which enables noninvasive real-time three-dimensional (3-D) visualization for in vivo studies. The ill-posedness of the FMT reconstruction problem is one of the many challenges in the studies of FMT. In this paper, we propose a l(2,1)-norm optimization method using a priori information, mainly the structured sparsity of the fluorescent regions for FMT reconstruction. Compared to standard sparsity methods, the structured sparsity methods are often superior in reconstruction accuracy since the structured sparsity utilizes correlations or structures of the reconstructed image. To solve the problem effectively, the Nesterov's method was used to accelerate the computation. To evaluate the performance of the proposed l(2,1)-norm method, numerical phantom experiments and in vivo mouse experiments are conducted. The results show that the proposed method not only achieves accurate and desirable fluorescent source reconstruction, but also demonstrates enhanced robustness to noise. (C) 2016 Optical Society of America
关键词Image Reconstruction Techniques Spectroscopy Fluorescence And Luminescence Tomography
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
DOI10.1364/BOE.7.002342
关键词[WOS]DIFFUSE OPTICAL TOMOGRAPHY ; ELEMENT BASED TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; BIOLUMINESCENCE TOMOGRAPHY ; SPARSITY REGULARIZATION ; ALGORITHM ; LIGHT ; INFORMATION ; MICROSCOPY ; TISSUE
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China(81571836 ; Fundamental Research Funds for the Central Universities(2015JBM026) ; China Postdoctoral Science Foundation(2015M570032 ; Beijing Natural Science Foundation(7164270 ; Open Research Project from SKLMCCS(20150103) ; 81227901 ; 2015T80155) ; 20140491524) ; 61231004 ; 61501462)
WOS研究方向Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000377514000023
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/12187
专题中国科学院分子影像重点实验室
通讯作者Liu, Jie
作者单位1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, 3 Shangyuancun, Beijing 100044, Peoples R China
2.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Inst Automat, Beijing Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
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GB/T 7714
Jiang, Shixin,Liu, Jie,An, Yu,et al. Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction[J]. BIOMEDICAL OPTICS EXPRESS,2016,7(6):2342-2359.
APA Jiang, Shixin.,Liu, Jie.,An, Yu.,Zhang, Guanglei.,Ye, Jinzuo.,...&Tian, Jie.(2016).Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction.BIOMEDICAL OPTICS EXPRESS,7(6),2342-2359.
MLA Jiang, Shixin,et al."Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction".BIOMEDICAL OPTICS EXPRESS 7.6(2016):2342-2359.
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