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DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy
Du, Yang1; Jiang, Qiao2,3; Beziere, Nicolas4,5; Song, Linlin2; Zhang, Qian1; Peng, Dong1; Chi, Chongwei1; Yang, Xin1; Guo, Hongbo2; Diot, Gael4,5; Ntziachristos, Vasilis4,5; Ding, Baoquan2; Tian, Jie1
2016-12-07
发表期刊ADVANCED MATERIALS
卷号28期号:45页码:10000-10007
文章类型Article
摘要A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
WOS标题词Science & Technology ; Physical Sciences ; Technology
DOI10.1002/adma.201601710
关键词[WOS]OPTICAL CONTRAST AGENT ; PHOTOACOUSTIC TOMOGRAPHY ; LIVING MICE ; CANCER ; NANOPARTICLES ; TISSUE ; NANOMATERIALS ; DELIVERY ; ORIGAMI ; FLUORESCENT
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China(81227901 ; Research and Development Program of China (973)(2014CB748600 ; Beijing Natural Science Foundation(L140008) ; Beijing Municipal Science & Technology Commission(Z161100000116036 ; CAS Interdisciplinary Innovation Team ; Cluster of Excellence "Nanosystem Initiative Munich" ; Deutsche Forschungsgemeinschaft (DFG)(SFB-824) ; ERC(233161) ; Chinese Academy of Sciences(YZ201359) ; 81470083 ; 2015CB755500 ; Z151100001615012) ; 61231004 ; 2012CB934000) ; 21573051 ; 81501594)
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号WOS:000392725200011
引用统计
被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/14362
专题中国科学院分子影像重点实验室
作者单位1.Chinese Acad Sci, Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Inst Automat, Beijing 100190, Peoples R China
2.Natl Ctr Nanosci & Technol, CAS Key Lab Nanosyst & Hierarch Fabricat, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing 100190, Peoples R China
4.Helmholtz Zentrum Munchen, Inst Biol & Med Imaging, D-85764 Neuherberg, Germany
5.Tech Univ Munich, D-85764 Neuherberg, Germany
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Du, Yang,Jiang, Qiao,Beziere, Nicolas,et al. DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy[J]. ADVANCED MATERIALS,2016,28(45):10000-10007.
APA Du, Yang.,Jiang, Qiao.,Beziere, Nicolas.,Song, Linlin.,Zhang, Qian.,...&Tian, Jie.(2016).DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy.ADVANCED MATERIALS,28(45),10000-10007.
MLA Du, Yang,et al."DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy".ADVANCED MATERIALS 28.45(2016):10000-10007.
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