CASIA OpenIR  > 脑网络组研究中心
Multimodal connectivity-based parcellation reveals a shell-core dichotomy of the human nucleus accumbens
Xia, Xiaoluan1; Fan, Lingzhong2; Cheng, Chen1; Eickhoff, Simon B.4,5; Chen, Junjie1; Li, Haifang1; Jiang, Tianzi2,3,6,7
2017-08-01
发表期刊HUMAN BRAIN MAPPING
卷号38期号:8页码:3878-3898
文章类型Review
摘要The subdifferentiation of the nucleus accumbens (NAc) has been extensively studied using neuroanatomy and histochemistry, yielding a well-accepted dichotomic shell/core architecture that reflects dissociable roles, such as in reward and aversion, respectively. However, in vivo parcellation of these structures in humans has been rare, potentially impairing future research into the structural and functional characteristics and alterations of putative NAc subregions. Here, we used three complementary parcellation schemes based on tractography, task-independent functional connectivity, and task-dependent co-activation to investigate the regional differentiation within the NAc. We found that a 2-cluster solution with shell-like and core-like subdivisions provided the best description of the data and was consistent with the earlier anatomical shell/core architecture. The consensus clusters from this optimal solution, which was based on the three schemes, were used as the final parcels for the subsequent connection analyses. The resulting connectivity patterns presented inter-hemispheric symmetry, convergence and divergence across the modalities, and, most importantly, clearly distinct patterns between the two subregions. This convergent connectivity patterns also confirmed the connections in animal models, supporting views that the two subregions could have antagonistic roles in some circumstances. Finally, the identified parcels should be helpful in further neuroimaging studies of the NAc. Hum Brain Mapp 38:3878-3898, 2017. (c) 2017 Wiley Periodicals, Inc.
关键词Nucleus Accumbens Connectivity-based Parcellation Tractography Functional Connectivity Meta-analytic Connectivity Modeling
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1002/hbm.23636
关键词[WOS]HUMAN CONNECTOME PROJECT ; ANTERIOR CINGULATE CORTEX ; INFERIOR PARIETAL LOBULE ; DEEP BRAIN-STIMULATION ; CONVERGENT FUNCTIONAL ARCHITECTURE ; INFRALIMBIC PREFRONTAL CORTEX ; VENTRAL TEGMENTAL AREA ; HUMAN FRONTAL POLE ; BASAL GANGLIA ; ORBITOFRONTAL CORTEX
收录类别SCI
语种英语
项目资助者National Key Basic Research and Development Program (973)(2011CB707801 ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDB02030300) ; Natural Science Foundation of China(91432302 ; Deutsche Forschungsgemeinschaft(EI 816/4-1 ; National Institute of Mental Health(R01-MH074457) ; Helmholtz Portfolio Theme "Supercomputing and Modeling for the Human Brain" ; European Union Seventh Framework Programme(604102) ; Beijing Municipal Science & Technology Commission(Z161100000216139) ; 2012CB720702) ; 91132301 ; EI 816/6-1) ; 81501179 ; 81270020 ; 61373101 ; 61472270 ; 61402318)
WOS研究方向Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000404963900009
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/15248
专题脑网络组研究中心
作者单位1.Taiyuan Univ Technol, Coll Comp Sci & Technol, Taiyuan 030600, Peoples R China
2.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China
4.Res Ctr Juelich, Inst Neurosci & Med INM 1, D-52425 Julich, Germany
5.Heinrich Heine Univ Dusseldorf, Inst Clin Neurosci & Med Psychol, D-40225 Dusseldorf, Germany
6.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Automat, Beijing 100190, Peoples R China
7.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
推荐引用方式
GB/T 7714
Xia, Xiaoluan,Fan, Lingzhong,Cheng, Chen,et al. Multimodal connectivity-based parcellation reveals a shell-core dichotomy of the human nucleus accumbens[J]. HUMAN BRAIN MAPPING,2017,38(8):3878-3898.
APA Xia, Xiaoluan.,Fan, Lingzhong.,Cheng, Chen.,Eickhoff, Simon B..,Chen, Junjie.,...&Jiang, Tianzi.(2017).Multimodal connectivity-based parcellation reveals a shell-core dichotomy of the human nucleus accumbens.HUMAN BRAIN MAPPING,38(8),3878-3898.
MLA Xia, Xiaoluan,et al."Multimodal connectivity-based parcellation reveals a shell-core dichotomy of the human nucleus accumbens".HUMAN BRAIN MAPPING 38.8(2017):3878-3898.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xia, Xiaoluan]的文章
[Fan, Lingzhong]的文章
[Cheng, Chen]的文章
百度学术
百度学术中相似的文章
[Xia, Xiaoluan]的文章
[Fan, Lingzhong]的文章
[Cheng, Chen]的文章
必应学术
必应学术中相似的文章
[Xia, Xiaoluan]的文章
[Fan, Lingzhong]的文章
[Cheng, Chen]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。