CASIA OpenIR  > 中国科学院分子影像重点实验室
Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome
Lin, Yusong1,2; Bai, Yan3,4,5,6; Liu, Peng7; Yang, Xuejuan7; Qin, Wei7; Gu, Jianqin4,8; Ding, Degang4,9; Tian, Jie10; Wang, Meiyun3,4,5,6,8
2017-09-19
发表期刊PLOS ONE
卷号12期号:9
文章类型Article
摘要The purpose of this study was to explore the neural mechanism in Chronic prostatitis/Chronic pelvic pain syndrome (CP/CPPS) using resting-state functional magnetic resonance imaging. The functional magnetic resonance imaging was performed on 31 male CP/CPPS-patients and 31 age and education matched male healthy controls on a 3-T magnetic resonance imaging unit. A two-sample t-test was adopted to reveal the regional homogeneity between the patients and healthy controls. The mean regional homogeneity values in the alerted brain regions of patients were correlated with the clinical measurements by using Pearson's correlation analyses. The CP/CPPS-patients had significantly decreased regional homogeneity in the bilateral anterior cingulate cortices, insular cortices and right medial prefrontal cortex, while significantly increased regional homogeneity in the brainstem and right thalamus compared with the healthy controls. In the CP/CPPSpatients, the mean regional homogeneity value in the left anterior cingulate cortex, bilateral insular cortices and brainstem were respectively correlated with the National Institutes of Health Chronic Prostatitis Symptom Index total score and pain subscale. These brain regions are important in the pain modulation process. Therefore, an impaired pain modulatory system, either by decreased descending pain inhibition or enhanced pain facilitation, may explain the pain symptoms in CP/CPPS.
WOS标题词Science & Technology
DOI10.1371/journal.pone.0184896
关键词[WOS]OPIOID RECEPTOR AVAILABILITY ; ANTERIOR CINGULATE CORTEX ; NATIONAL-INSTITUTES ; SYMPTOM INDEX ; BACK-PAIN ; FIBROMYALGIA ; FMRI ; HEALTH ; UNPLEASANTNESS ; ACTIVATION
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China(31470047 ; Henan Province Scientific and Technological Innovation Talents Project(164200510014) ; Henan Province Scientific and Technological Cooperation Project(152106000014) ; Key Project of Henan Medical Science and Technology Project(201501011) ; 81641168 ; 81271565 ; 81601466 ; 81271644 ; 81471811)
WOS研究方向Science & Technology - Other Topics
WOS类目Multidisciplinary Sciences
WOS记录号WOS:000411166600050
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/20734
专题中国科学院分子影像重点实验室
作者单位1.Zhengzhou Univ, Cooperat Innovat Ctr Internet Healthcare, Zhengzhou, Henan, Peoples R China
2.Zhengzhou Univ, Sch Software & Appl Technol, Zhengzhou, Henan, Peoples R China
3.Zhengzhou Univ, Peoples Hosp, Dept Radiol, Zhengzhou, Henan, Peoples R China
4.Henan Prov Peoples Hosp, Zhengzhou, Henan, Peoples R China
5.Henan Key Lab Med Imaging Neurol Dis, Xinjiang, Peoples R China
6.Henan Univ, Med Sch, Zhengzhou, Henan, Peoples R China
7.Xidian Univ, Sch Life Sci & Technol, Xian, Shaanxi, Peoples R China
8.Zhengzhou Univ, Peoples Hosp, Henan Prov Clin Big Data Anal & Serv Engn Res Ctr, Zhengzhou, Henan, Peoples R China
9.Zhengzhou Univ, Peoples Hosp, Dept Urol, Zhengzhou, Henan, Peoples R China
10.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Lin, Yusong,Bai, Yan,Liu, Peng,et al. Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome[J]. PLOS ONE,2017,12(9).
APA Lin, Yusong.,Bai, Yan.,Liu, Peng.,Yang, Xuejuan.,Qin, Wei.,...&Wang, Meiyun.(2017).Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome.PLOS ONE,12(9).
MLA Lin, Yusong,et al."Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome".PLOS ONE 12.9(2017).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Lin, Yusong]的文章
[Bai, Yan]的文章
[Liu, Peng]的文章
百度学术
百度学术中相似的文章
[Lin, Yusong]的文章
[Bai, Yan]的文章
[Liu, Peng]的文章
必应学术
必应学术中相似的文章
[Lin, Yusong]的文章
[Bai, Yan]的文章
[Liu, Peng]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。