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Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population
Yang, Yongfeng1,2,3; Yu, Hongyan2; Li, Wenqiang2,3; Liu, Bing4; Zhang, Hongxing2,3; Ding, Shuang2,3; Lu, Yanli2,3; Jiang, Tianzi1,4,5,6; Lv, Luxian2,3,7
Source PublicationBEHAVIORAL AND BRAIN FUNCTIONS
2018-01-03
Volume14
SubtypeArticle
AbstractBackground: Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Dopamine dysfunction is one of the pathogenesis of SZ. However, the relationship between CDNF2 and SZ has not been previously investigated. We speculated that CDNF2 may be a susceptibility factor for SZ.
KeywordCdnf2 Polymorphism Panss Schizophrenia
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1186/s12993-017-0133-4
WOS KeywordGENOME-WIDE ASSOCIATION ; PARKINSONS-DISEASE ; RAT MODEL ; RISK ; LOCI ; GENE ; DISORDER ; PROTECTS ; MICE
Indexed BySCI ; SSCI
Language英语
Funding OrganizationNational Natural Science Foundation of China(81371472 ; National Key Basic Research and Development Program (973)(2011CB707800) ; Medical Science and Technology Foundation of Henan Province(201702131) ; National Laboratory of Pattern Recognition (NLPR)(201600010) ; U1404811)
WOS Research AreaBehavioral Sciences ; Neurosciences & Neurology
WOS SubjectBehavioral Sciences ; Neurosciences
WOS IDWOS:000419152700001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/20756
Collection脑网络组研究中心
Affiliation1.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu, Sichuan, Peoples R China
2.Xinxiang Med Univ, Dept Psychiat, Henan Mental Hosp, Affiliated Hosp 2, Xinxiang, Peoples R China
3.Xinxiang Med Univ, Henan Key Lab Biol Psychiat, Xinxiang, Peoples R China
4.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China
5.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China
6.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
7.Xinxiang Med Univ, Dept Psychiat, Affiliated Hosp 2, 388 Jianshe Middle Rd, Xinxiang 453002, Peoples R China
Recommended Citation
GB/T 7714
Yang, Yongfeng,Yu, Hongyan,Li, Wenqiang,et al. Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population[J]. BEHAVIORAL AND BRAIN FUNCTIONS,2018,14.
APA Yang, Yongfeng.,Yu, Hongyan.,Li, Wenqiang.,Liu, Bing.,Zhang, Hongxing.,...&Lv, Luxian.(2018).Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population.BEHAVIORAL AND BRAIN FUNCTIONS,14.
MLA Yang, Yongfeng,et al."Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population".BEHAVIORAL AND BRAIN FUNCTIONS 14(2018).
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