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Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population
Yang, Yongfeng1,2,3; Yu, Hongyan2; Li, Wenqiang2,3; Liu, Bing4; Zhang, Hongxing2,3; Ding, Shuang2,3; Lu, Yanli2,3; Jiang, Tianzi1,4,5,6; Lv, Luxian2,3,7
2018-01-03
发表期刊BEHAVIORAL AND BRAIN FUNCTIONS
卷号14
文章类型Article
摘要Background: Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Dopamine dysfunction is one of the pathogenesis of SZ. However, the relationship between CDNF2 and SZ has not been previously investigated. We speculated that CDNF2 may be a susceptibility factor for SZ.
关键词Cdnf2 Polymorphism Panss Schizophrenia
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1186/s12993-017-0133-4
关键词[WOS]GENOME-WIDE ASSOCIATION ; PARKINSONS-DISEASE ; RAT MODEL ; RISK ; LOCI ; GENE ; DISORDER ; PROTECTS ; MICE
收录类别SCI ; SSCI
语种英语
项目资助者National Natural Science Foundation of China(81371472 ; National Key Basic Research and Development Program (973)(2011CB707800) ; Medical Science and Technology Foundation of Henan Province(201702131) ; National Laboratory of Pattern Recognition (NLPR)(201600010) ; U1404811)
WOS研究方向Behavioral Sciences ; Neurosciences & Neurology
WOS类目Behavioral Sciences ; Neurosciences
WOS记录号WOS:000419152700001
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文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/20756
专题脑网络组研究中心
作者单位1.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu, Sichuan, Peoples R China
2.Xinxiang Med Univ, Dept Psychiat, Henan Mental Hosp, Affiliated Hosp 2, Xinxiang, Peoples R China
3.Xinxiang Med Univ, Henan Key Lab Biol Psychiat, Xinxiang, Peoples R China
4.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China
5.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China
6.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
7.Xinxiang Med Univ, Dept Psychiat, Affiliated Hosp 2, 388 Jianshe Middle Rd, Xinxiang 453002, Peoples R China
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GB/T 7714
Yang, Yongfeng,Yu, Hongyan,Li, Wenqiang,et al. Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population[J]. BEHAVIORAL AND BRAIN FUNCTIONS,2018,14.
APA Yang, Yongfeng.,Yu, Hongyan.,Li, Wenqiang.,Liu, Bing.,Zhang, Hongxing.,...&Lv, Luxian.(2018).Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population.BEHAVIORAL AND BRAIN FUNCTIONS,14.
MLA Yang, Yongfeng,et al."Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population".BEHAVIORAL AND BRAIN FUNCTIONS 14(2018).
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