CASIA OpenIR  > 中国科学院分子影像重点实验室
The combination design for open and endoscopic surgery using fluorescence molecular imaging technology
Yamin Mao1; Shixin Jiang2; Jinzuo Ye1; Yu An2; Xin Yang1; Chongwei Chi1; Jie Tian1
Conference NameSPIE Photonics West
Conference Date2015.02.07-08
Conference PlaceSan Francisco
AbstractFor clinical surgery, it is still a challenge to objectively determine tumor margins during surgery. With the development of medical imaging technology, fluorescence molecular imaging (FMI) method can provide real-time intraoperative tumor margin information. Furthermore, surgical navigation system based on FMI technology plays an important role for the aid of surgeons’ precise tumor margin decision. However, detection depth is the most limitation exists in the FMI technique and the method convenient for either macro superficial detection or micro deep tissue detection is needed. In this study, we combined advantages of both open surgery and endoscopic imaging systems with FMI technology. Indocyanine green (ICG) experiments were performed to confirm the feasibility of fluorescence detection in our system. Then, the ICG signal was photographed in the detection area with our system. When the system connected with endoscope lens, the minimum quantity of ICG detected by our system was 0.195 ug. For aspect of C mount lens, the sensitivity of ICG detection with our system was 0.195ug. Our experiments results proved that it was feasible to detect fluorescence images with this combination method. Our system shows great potential in the clinical applications of precise dissection of various tumors.
KeywordIntraoperative Image-guided Surgery Fluorescence Molecular Imaging Surgical Navigation System Indocyanine Green Endoscopy
Document Type会议论文
Affiliation1.Key Laboratory of Molecular Imaging, Institute of Chinese Academy of Sciences, Beijing 100190,China
2.The Department of Biomedical Engineering, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China
Recommended Citation
GB/T 7714
Yamin Mao,Shixin Jiang,Jinzuo Ye,et al. The combination design for open and endoscopic surgery using fluorescence molecular imaging technology[C],2015.
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