Spinal Cord Stimulation Frequency Influences the Hemodynamic Response in Patients with Disorders of Consciousness

doi:10.1007/s12264-018-0252-4

	Spinal Cord Stimulation Frequency Influences the Hemodynamic Response in Patients with Disorders of Consciousness
	Si, Juanning 1; Dang, Yuanyuan 2; Zhang, Yujin3,4 ; Li, Yaxin 1; Zhang, Wenyue 1; Yang, Yi 2; Cui, Yue3,4 ; Lou, Xiaoping 1; He, Jianghong 2; Jiang, Tianzi3,4,5,6,7
发表期刊	NEUROSCIENCE BULLETIN
	2018-08-01
卷号	34 期号:4 页码:659-667
文章类型	Article
摘要	Spinal cord stimulation (SCS) is a promising technique for treating disorders of consciousness (DOCs). However, differences in the spatio-temporal responsiveness of the brain under varied SCS parameters remain unclear. In this pilot study, functional near-infrared spectroscopy was used to measure the hemodynamic responses of 10 DOC patients to different SCS frequencies (5 Hz, 10 Hz, 50 Hz, 70 Hz, and 100 Hz). In the prefrontal cortex, a key area in consciousness circuits, we found significantly increased hemodynamic responses at 70 Hz and 100 Hz, and significantly different hemodynamic responses between 50 Hz and 70 Hz/100 Hz. In addition, the functional connectivity between prefrontal and occipital areas was significantly improved with SCS at 70 Hz. These results demonstrated that SCS modulates the hemodynamic responses and long-range connectivity in a frequency-specific manner (with 70 Hz apparently better), perhaps by improving the cerebral blood volume and information transmission through the reticular formation-thalamus-cortex pathway.
关键词	Disorder Of Consciousness Spinal Cord Stimulation Frequency Functional Near-infrared Spectroscopy Hemodynamic Response
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1007/s12264-018-0252-4
关键词[WOS]	NEAR-INFRARED SPECTROSCOPY ; VEGETATIVE STATE ; WORKING-MEMORY ; BRAIN-INJURY ; PARAMETERS ; PET
收录类别	SCI
语种	英语
项目资助者	National Key Research and Development Program of China(2017YFB1002502) ; National Natural Science Foundation of China(81501550 ; Cross Training (Shipei) Project of High-Caliber Talents in Beijing Municipal Institutions ; Supplementary and Supportive Project for Teachers at Beijing Information Science and Technology University(5029011103) ; School Scientific Research Project at Beijing Information Science and Technology University(1825010) ; Beijing Municipal Science and Technology Commission(Z161100000516165) ; Shenzhen Peacock Plan(KQTD2015033016104926) ; Guangdong Pearl River Talents Plan Innovative and Entrepreneurial Team grant(2016ZT06S220) ; 81600919 ; 31771076)
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000440164500008
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/21854
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.Beijing Informat Sci & Technol Univ, Sch Instrumentat Sci & Optoelect Engn, Beijing 100192, Peoples R China 2.Peoples Liberat Army Gen Hosp, Dept Neurosurg, Beijing 100700, Peoples R China 3.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 5.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 625014, Sichuan, Peoples R China 6.Chinese Acad Sci, Inst Automat, Ctr Excellence Brain Sci, Beijing 100190, Peoples R China 7.Univ Queensland, Queensland Brain Inst, St Lucia, Qld 4072, Australia
推荐引用方式 GB/T 7714	Si, Juanning,Dang, Yuanyuan,Zhang, Yujin,et al. Spinal Cord Stimulation Frequency Influences the Hemodynamic Response in Patients with Disorders of Consciousness[J]. NEUROSCIENCE BULLETIN,2018,34(4):659-667.
APA	Si, Juanning.,Dang, Yuanyuan.,Zhang, Yujin.,Li, Yaxin.,Zhang, Wenyue.,...&Jiang, Tianzi.(2018).Spinal Cord Stimulation Frequency Influences the Hemodynamic Response in Patients with Disorders of Consciousness.NEUROSCIENCE BULLETIN,34(4),659-667.
MLA	Si, Juanning,et al."Spinal Cord Stimulation Frequency Influences the Hemodynamic Response in Patients with Disorders of Consciousness".NEUROSCIENCE BULLETIN 34.4(2018):659-667.