Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging | |
He, Pan1,2; Huang, Tao1; Fang, Cheng1; Su, Song1; Tian, Jie3 ; Xia, XianMing1; Li, Bo1
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| Source Publication | PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
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| ISSN | 1572-1000 |
| 2019-03-01 | |
| Volume | 25Pages:417-420 |
| Corresponding Author | Xia, XianMing(xxm6202@126.com) ; Li, Bo(liboer2002@126.com) |
| Abstract | Background/purpose: Intraoperative fluorescence imaging with indocyanine green (ICG) plays a significant role in the identification of hepatocellular carcinoma (HCC) during Hepatectomy. Despite that, few researchers have reported using ICG fluorescence imaging to detect extrahepatic metastases. Herein, we report the successful application of ICG fluorescence imaging in the detection of extrahepatic metastatic lesions from primary liver cancer. Methods: In two HCC patients, a near-infrared fluorescence imaging system was used to intraoperatively examine the abdominal cavity for implantation metastasis after hepatectomy of the primary tumor, following preoperative intravenous infusion with ICG. Results: In the first case, the abdominal cavity implantation metastasis exhibited intense fluorescence and clear boundaries of tumors during abdominal tumor resection, and there was no fluorescence in the resection margin. In the second case, a new lesion that was not detected by preoperative imaging examination was found in the omentum by ICG fluorescence imaging. Intraoperative rapid freezing pathology showed that it was an adenocarcinoma. Accordingly, we revised the tumor staging. Conclusion: ICG fluorescence imaging can not only detect intrahepatic metastases, but also extrahepatic metastases. Furthermore, it can help surgeons correct tumor staging during surgery. |
| Keyword | Indocyanine green Fluorescence imaging Implantation metastasis Hepatocellular carcinoma |
| DOI | 10.1016/j.pdpdt.2019.01.031 |
| WOS Keyword | RESECTION ; RECURRENCE |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Scientific and technological strategic cooperation Foundation ; Peoples Government of luzhou city, China[2017LZXNYD-J07] ; Scientific and technological strategic cooperation Foundation ; Peoples Government of luzhou city, China[2017LZXNYD-J07] |
| Funding Organization | Scientific and technological strategic cooperation Foundation ; Peoples Government of luzhou city, China |
| WOS Research Area | Oncology |
| WOS Subject | Oncology |
| WOS ID | WOS:000465059600064 |
| Publisher | ELSEVIER SCIENCE BV |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ia.ac.cn/handle/173211/24931 |
| Collection | 中国科学院分子影像重点实验室 |
| Corresponding Author | Xia, XianMing; Li, Bo |
| Affiliation | 1.Southwest Med Univ, Affiliated Hosp, Dept Hepatobiliary Surg, Luzhou 646000, Peoples R China 2.Southwest Med Univ, Affiliated Hosp, Dept Anesthesiol, Luzhou 646000, Peoples R China 3.Chinese Acad Sci, Key Lab Mol Imaging, Inst Automat, Beijing 100190, Peoples R China |
| Recommended Citation GB/T 7714 | He, Pan,Huang, Tao,Fang, Cheng,et al. Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging[J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,2019,25:417-420. |
| APA | He, Pan.,Huang, Tao.,Fang, Cheng.,Su, Song.,Tian, Jie.,...&Li, Bo.(2019).Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging.PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,25,417-420. |
| MLA | He, Pan,et al."Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging".PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 25(2019):417-420. |
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