CASIA OpenIR
Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy
Feng, Miao1; Lv, Ruichan1; Xiao, Liyang1; Hu, Bo1; Zhu, Shouping1; He, Fei2; Yang, Piaoping2; Tian, Jie1,3
Source PublicationINORGANIC CHEMISTRY
ISSN0020-1669
2018-12-03
Volume57Issue:23Pages:14594-14602
Corresponding AuthorLv, Ruichan(rclv@xidian.edu.cn) ; Yang, Piaoping(yangpiaoping@hrbeu.edu.cn) ; Tian, Jie(jie.tian@ia.ac.cn)
AbstractGenerally, luminescence quenching at high doping concentrations typically limits the concentration of doped ions in the lanthanide material to less than 0.05-20 mol %, and this is still a major hindrance in designing nanoplatforms with improved brightness. In this research, a nanoplatform capable of dual-modal imaging and synergetic antitumor cells therapy was designed. NaYF4:x%Er@NaXF4 (x = 5, 25, 50, and 100; X = Lu and Y) core@shell nanoparticles with Er3+ ion concentration up to 100 mol % were synthesized, and the luminescence properties under near-infrared (NIR) excitation were detected. The results show the strong coupled of surface and concentration quenching effects in upconversion nanoparticles (UCNP). Upconversion luminescence (UCL) and NIR-II emission intensity increased with negligible concentration quenching effect under 980 and 800 nm NIR lasers because of the growth of epitaxial shells. Therefore, the enhanced red luminescence transfers energy to photosensitizer ZnPc as the photodynamic therapy (PDT) agent for tumor inhibition efficacy.
DOI10.1021/acs.inorgchem.8b02257
WOS KeywordUP-CONVERSION NANOPARTICLES ; ENERGY-TRANSFER ; LIGHT ; SHELL ; NANOCRYSTALS ; LUMINESCENCE ; SURFACE ; DESIGN ; NANOPHOSPHOR ; STRATEGY
Indexed BySCI
Language英语
Funding ProjectNatural Science Foundation of China[NSFC 81227901] ; Natural Science Foundation of China[81772011] ; Natural Science Foundation of China[81801744] ; National Key R&D Program of China[2016YFC0102000] ; National Key R&D Program of China[2017YFA0205202] ; National Key R&D Program of China[2017YFA0205200] ; Fundamental Research Funds for the Central Universities[XJS17011] ; Fundamental Research Funds for the Central Universities[JBX181202]
Funding OrganizationNatural Science Foundation of China ; National Key R&D Program of China ; Fundamental Research Funds for the Central Universities
WOS Research AreaChemistry
WOS SubjectChemistry, Inorganic & Nuclear
WOS IDWOS:000452344400019
PublisherAMER CHEMICAL SOC
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/25670
Collection中国科学院自动化研究所
Corresponding AuthorLv, Ruichan; Yang, Piaoping; Tian, Jie
Affiliation1.Xidian Univ, Sch Life Sci & Technol, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China
2.Harbin Engn Univ, Coll Mat Sci & Chem Engn, Key Lab Superlight Mat & Surface Technol, Minist Educ, Harbin 150001, Heilongjiang, Peoples R China
3.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, Beijing 100190, Peoples R China
Corresponding Author AffilicationInstitute of Automation, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Feng, Miao,Lv, Ruichan,Xiao, Liyang,et al. Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy[J]. INORGANIC CHEMISTRY,2018,57(23):14594-14602.
APA Feng, Miao.,Lv, Ruichan.,Xiao, Liyang.,Hu, Bo.,Zhu, Shouping.,...&Tian, Jie.(2018).Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy.INORGANIC CHEMISTRY,57(23),14594-14602.
MLA Feng, Miao,et al."Highly Erbium-Doped Nanoplatform with Enhanced Red Emission for Dual-Modal Optical-Imaging-Guided Photodynamic Therapy".INORGANIC CHEMISTRY 57.23(2018):14594-14602.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Feng, Miao]'s Articles
[Lv, Ruichan]'s Articles
[Xiao, Liyang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Feng, Miao]'s Articles
[Lv, Ruichan]'s Articles
[Xiao, Liyang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Feng, Miao]'s Articles
[Lv, Ruichan]'s Articles
[Xiao, Liyang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.