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Improved generative adversarial networks using the total gradient loss for the resolution enhancement of fluorescence images
Zhang, Chong1,2,3; Wang, Kun1,2,3; An, Yu1,2,3; He, Kunshan1,2,3; Tong, Tong1,2,3; Tian, Jie1,2,3,4
发表期刊BIOMEDICAL OPTICS EXPRESS
ISSN2156-7085
2019-09-01
卷号10期号:9页码:4742-4756
摘要

Because of the optical properties of medical fluorescence images (FIs) and hardware limitations, light scattering and diffraction constrain the image quality and resolution. In contrast to device-based approaches, we developed a post-processing method for Fl resolution enhancement by employing improved generative adversarial networks. To overcome the drawback of fake texture generation, we proposed total gradient loss for network training. Fine-tuning training procedure was applied to further improve the network architecture. Finally, a more agreeable network for resolution enhancement was applied to actual FIs to produce sharper and clearer boundaries than in the original images. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

DOI10.1364/BOE.10.004742
收录类别SCI
语种英语
资助项目Chinese Academy of Sciences[YJKYYQ20180048] ; Chinese Academy of Sciences[XDBS01030200] ; Chinese Academy of Sciences[KFJ-STS-ZDTP-059] ; Ministry of Science and Technology of the People's Republic of China[2018YFC0910602] ; Ministry of Science and Technology of the People's Republic of China[2016YFC0103803] ; Ministry of Science and Technology of the People's Republic of China[2015CB755500] ; Ministry of Science and Technology of the People's Republic of China[2017YFA0205200] ; Chinese Academy of Sciences[QYZDJ-SSW-JSC005] ; Chinese Academy of Sciences[GJJSTD20170004] ; National Natural Science Foundation of China[61671449] ; National Natural Science Foundation of China[81527805] ; National Natural Science Foundation of China[81227901] ; National Natural Science Foundation of China[81227901] ; National Natural Science Foundation of China[81527805] ; National Natural Science Foundation of China[61671449] ; Chinese Academy of Sciences[GJJSTD20170004] ; Chinese Academy of Sciences[QYZDJ-SSW-JSC005] ; Ministry of Science and Technology of the People's Republic of China[2017YFA0205200] ; Ministry of Science and Technology of the People's Republic of China[2015CB755500] ; Ministry of Science and Technology of the People's Republic of China[2016YFC0103803] ; Ministry of Science and Technology of the People's Republic of China[2018YFC0910602] ; Chinese Academy of Sciences[KFJ-STS-ZDTP-059] ; Chinese Academy of Sciences[XDBS01030200] ; Chinese Academy of Sciences[YJKYYQ20180048]
WOS研究方向Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000484088600029
出版者OPTICAL SOC AMER
七大方向——子方向分类医学影像处理与分析
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/25834
专题中国科学院分子影像重点实验室
通讯作者Tian, Jie
作者单位1.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100049, Peoples R China
3.Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China
4.BUAA CCMU Adv Innovat Ctr Big Data Based Precis M, Beijing 100083, Peoples R China
第一作者单位中国科学院分子影像重点实验室
通讯作者单位中国科学院分子影像重点实验室
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GB/T 7714
Zhang, Chong,Wang, Kun,An, Yu,et al. Improved generative adversarial networks using the total gradient loss for the resolution enhancement of fluorescence images[J]. BIOMEDICAL OPTICS EXPRESS,2019,10(9):4742-4756.
APA Zhang, Chong,Wang, Kun,An, Yu,He, Kunshan,Tong, Tong,&Tian, Jie.(2019).Improved generative adversarial networks using the total gradient loss for the resolution enhancement of fluorescence images.BIOMEDICAL OPTICS EXPRESS,10(9),4742-4756.
MLA Zhang, Chong,et al."Improved generative adversarial networks using the total gradient loss for the resolution enhancement of fluorescence images".BIOMEDICAL OPTICS EXPRESS 10.9(2019):4742-4756.
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