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Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview
Huang, Jianjie1; Zhuo, Chuanjun1,2,3,4,5; Song, Xueqin6; Li, Yachen3,4,5; Jing, Rixing7; Tian, Hongjun3,4,5; Wang, Lina3,4,5; Mao, Fuqiang5; Li, Shen5; Jiang, Ronghuan8; Chen, Suling1
Source PublicationJOURNAL OF NERVOUS AND MENTAL DISEASE
ISSN0022-3018
2019-07-01
Volume207Issue:7Pages:555-560
Corresponding AuthorZhuo, Chuanjun(chuanjunzhuotjmh@163.com) ; Jiang, Ronghuan(jiangrh55@126.com) ; Chen, Suling(csl0577zxh@163.com)
AbstractDepressive symptoms can occur at any point in the duration of schizophrenia. However, we are unable to predict if or when depression will occur in schizophrenic patients. Simultaneously, the standard treatment of depression in schizophrenic patients is the combination of antidepressants and antipsychotics, which has been minimally effective for most patients. Based on several studies, we hypothesized the existence of depressive-type schizophrenia and reviewed the substantial evidence supporting the hypothesis of depressive-type schizophrenia. Simultaneously, we propose technical methods to explore the neuropathology of depressive-type schizophrenia in order to identify the disease during its early stages and to predict how patients will respond to the standard treatment strategies. We believe that the new classification of depressive-type schizophrenia will differentiate it from other forms of depression. In return, this will aid in the discovery of new therapeutic strategies for combatting this disease.
KeywordDepressive-type schizophrenia magnetic resonance imaging genetics deep learning classifier
DOI10.1097/NMD.0000000000001004
WOS KeywordPREFRONTAL CORTEX ; SYMPTOMS ; DISORDER ; ANTIDEPRESSANTS ; ANTIPSYCHOTICS ; PSYCHOSIS ; ANXIETY
Indexed BySCI
Language英语
Funding ProjectTianjin Health Bureau Foundation[2014KR02] ; National Natural Science Foundation of China[81871052] ; Key Projects of the Natural Science Foundation of Tianjin, China[17JCZDJC35700] ; Wenzhou Science and Technology Project[ZS2017011] ; Tianjin Health Bureau Foundation[2014KR02] ; National Natural Science Foundation of China[81871052] ; Key Projects of the Natural Science Foundation of Tianjin, China[17JCZDJC35700] ; Wenzhou Science and Technology Project[ZS2017011]
Funding OrganizationTianjin Health Bureau Foundation ; National Natural Science Foundation of China ; Key Projects of the Natural Science Foundation of Tianjin, China ; Wenzhou Science and Technology Project
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000475374300004
PublisherLIPPINCOTT WILLIAMS & WILKINS
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/26889
Collection模式识别国家重点实验室
Corresponding AuthorZhuo, Chuanjun; Jiang, Ronghuan; Chen, Suling
Affiliation1.Wenzhou Seventh Peoples Hosp, Dept Psychiat, 522 Xioshandong Rd, Wenzhou 325000, Peoples R China
2.Jining Med Univ, Dept Psychiat, Jining, Peoples R China
3.Tianjin Anding Hosp, Tianjin Mental Hlth Ctr, Dept Psychiatr Neuroimaging Genet Lab & Comorbid, Tianjin, Peoples R China
4.Tianjin Med Univ, Mental Hlth Teaching Hosp, Tianjin, Peoples R China
5.Tianjin Med Univ, Dept Psychiat, Tianjin, Peoples R China
6.Zhengzhou Univ, Affiliated Hosp 1, Dept Psychiat, Zhengzhou, Henan, Peoples R China
7.Chinese Acad Sci, Inst Automat, China Natl Key Lab, Dept Pattern Recognit, Beijing, Peoples R China
8.Chinese Peoples Liberat Army, Gen Hosp, Hosp 301, Dept Psychosomat Med, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Huang, Jianjie,Zhuo, Chuanjun,Song, Xueqin,et al. Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview[J]. JOURNAL OF NERVOUS AND MENTAL DISEASE,2019,207(7):555-560.
APA Huang, Jianjie.,Zhuo, Chuanjun.,Song, Xueqin.,Li, Yachen.,Jing, Rixing.,...&Chen, Suling.(2019).Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview.JOURNAL OF NERVOUS AND MENTAL DISEASE,207(7),555-560.
MLA Huang, Jianjie,et al."Does Depressive-Type Schizophrenia Exist? How Do We Prove It? An Updated Review and Overview".JOURNAL OF NERVOUS AND MENTAL DISEASE 207.7(2019):555-560.
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