Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation

doi:10.1016/j.neulet.2019.134289

	Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation
	Liu, Haiyang 1; Jian, Minyu 1; Liu, Shu2 ; Li, Ang2 ; Li, Shaowu 3; Fang, Jinghan 1; Liang, Fa 1; Liu, Bing2 ; Han, Ruquan 1
发表期刊	NEUROSCIENCE LETTERS
ISSN	0304-3940
	2019-08-10
卷号	707 页码:7
通讯作者	Han, Ruquan(ruquan.han@ccmu.edu.cn)
摘要	Functional connectivity patterns of the human brain show unique inherent or intrinsic characteristics at rest and when performing a task, similar to a fingerprint. However, whether this unique functional organization is preserved during sedation currently remains unknown. Here, we collected resting-state functional magnetic resonance imaging data from 20 subjects in each of three resting states: wakefulness, sedation, and recovery. We found that functional connectivity patterns could successfully identify individual subjects in any pair of the three resting states. In particular, identification analysis using functional connectivity patterns based on the frontoparietal network showed the highest success rates. Moreover, the overall individual difference in the frontoparietal-based functional connectivity patterns was much larger than that derived from other networks in each resting state. Collectively, our findings indicate that functional connectivity patterns within individual subjects are unique and relatively robust to brain state changes, regardless of dexmedetomidine-induced sedation.
关键词	Functional connectivity Sedation Dexmedetomidine Resting state Functional magnetic resonance Imaging
DOI	10.1016/j.neulet.2019.134289
关键词[WOS]	FINGERPRINTING IDENTIFYING INDIVIDUALS ; PROPOFOL-INDUCED LOSS ; STATE
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000486094600001
出版者	ELSEVIER IRELAND LTD
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/26990
专题	脑图谱与类脑智能实验室_脑网络组研究
通讯作者	Han, Ruquan
作者单位	1.Capital Med Univ, Beijing Tiantan Hosp, Dept Anesthesiol, Beijing, Peoples R China 2.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 3.Beijing Neurosurg Inst, Funct Imaging Ctr, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Liu, Haiyang,Jian, Minyu,Liu, Shu,et al. Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation[J]. NEUROSCIENCE LETTERS,2019,707:7.
APA	Liu, Haiyang.,Jian, Minyu.,Liu, Shu.,Li, Ang.,Li, Shaowu.,...&Han, Ruquan.(2019).Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation.NEUROSCIENCE LETTERS,707,7.
MLA	Liu, Haiyang,et al."Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation".NEUROSCIENCE LETTERS 707(2019):7.