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Significance of Resveratrol in Clinical Management of Chronic Diseases | |
Wahab, Awais1; Gao, Kuo1; Jia, Caixia1; Zhang, Feilong1; Tian, Guihua1,2; Murtaza, Ghulam1,3,4; Chen, Jianxin1 | |
发表期刊 | MOLECULES |
ISSN | 1420-3049 |
2017-08-01 | |
卷号 | 22期号:8页码:19 |
通讯作者 | Murtaza, Ghulam(gmdogar356@gmail.com) ; Chen, Jianxin(cjx@bucm.edu.cn) |
摘要 | Resveratrol could be beneficial to health and provides protection against a wide array of pathologies and age-associated problems, as evident from preclinical studies. However, a comparison of animal and human studies reveals that this dietary polyphenol cannot protect against metabolic diseases and their associated complications. The clinical outcomes are affected by many factors such as sample size. This article not only presents a comprehensive review of the current advances concerning the dose, the extent of absorption, interaction and toxicity of resveratrol in human studies, but also describes its therapeutic effects against several chronic diseases such as diabetes mellitus, obesity, cardiovascular diseases, cancer and aging and the related diseases. |
关键词 | pre-clinical studies clinical studies absorption toxicity diabetes mellitus obesity cardiovascular diseases cancer aging |
DOI | 10.3390/molecules22081329 |
关键词[WOS] | CORONARY-ARTERY-DISEASE ; GENETICALLY HETEROGENEOUS MICE ; RANDOMIZED CONTROLLED-TRIALS ; TYPE-2 DIABETES-MELLITUS ; BLOOD MONONUCLEAR-CELLS ; TRANS-RESVERATROL ; PRIMARY PREVENTION ; LIFE-SPAN ; IN-VITRO ; ALZHEIMERS-DISEASE |
收录类别 | SCI |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China[81403468] ; National Natural Science Foundation of China[81674050] ; National Natural Science Foundation of China[81522051] ; Beijing Nova Program[xx2014B049] ; Beijing Nova Program[XX2013032] ; National Natural Science Foundation of China[81403468] ; National Natural Science Foundation of China[81674050] ; National Natural Science Foundation of China[81522051] ; Beijing Nova Program[xx2014B049] ; Beijing Nova Program[xx2013032] |
项目资助者 | National Natural Science Foundation of China ; Beijing Nova Program |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Organic |
WOS记录号 | WOS:000408602900093 |
出版者 | MDPI AG |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/28031 |
专题 | 离退休人员 |
通讯作者 | Murtaza, Ghulam; Chen, Jianxin |
作者单位 | 1.Beijing Univ Chinese Med, Sch Preclin Med, Beijing 100029, Peoples R China 2.Beijing Univ Chinese Med, Dongzhimen Hosp, Beijing 100700, Peoples R China 3.COMSATS, Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan 4.Chinese Acad Sci, Inst Automat, Beijing 100029, Peoples R China |
通讯作者单位 | 中国科学院自动化研究所 |
推荐引用方式 GB/T 7714 | Wahab, Awais,Gao, Kuo,Jia, Caixia,et al. Significance of Resveratrol in Clinical Management of Chronic Diseases[J]. MOLECULES,2017,22(8):19. |
APA | Wahab, Awais.,Gao, Kuo.,Jia, Caixia.,Zhang, Feilong.,Tian, Guihua.,...&Chen, Jianxin.(2017).Significance of Resveratrol in Clinical Management of Chronic Diseases.MOLECULES,22(8),19. |
MLA | Wahab, Awais,et al."Significance of Resveratrol in Clinical Management of Chronic Diseases".MOLECULES 22.8(2017):19. |
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