Brainnetome: A new -ome to understand the brain and its disorders | |
Jiang, Tianzi1,2,3,4 | |
发表期刊 | NEUROIMAGE |
2013-10-15 | |
卷号 | 80页码:263-272 |
文章类型 | Article |
摘要 | The human brain can be studied as a hierarchy of complex networks on different temporal and spatial scales. On each scale, from gene, protein, synapse, neuron and microcircuit, to area, pathway and the whole brain, many advances have been made with the development of related techniques. Brain network studies on different temporal and spatial scales are booming. However, such studies have focused on single levels, and can only reflect limited aspects of how the brain is formed and how it works. Therefore, it is increasingly urgent to integrate a variety of techniques, methods and models, and to merge fragmented findings into a uniform research framework or platform. To this end, we have proposed the concept of the brainnetome and several related programs/projects have been launched in China. In this paper, we offer a brief review on the methodologies of the brainnetome, which include techniques on different scales, the brainnetome atlas, and methods of brain network analysis. We then take Alzheimer's disease and schizophrenia as examples to show how the brainnetome can be studied in neurological and psychiatric disorders. We also review the studies of how risk genes for brain diseases affect the brain networks. Finally, we summarize the challenges for the brainnetome, and what actions and measures have been taken to address these challenges in China. It is envisioned that the brainnetome will open new avenues and some long-standing issues may be solved by combining the brainnetome with other "omes". (C) 2013 Elsevier Inc. All rights reserved. |
关键词 | Brainnetome Brain Network Connectome Brain Connectivity Neuroimaging |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
关键词[WOS] | RESTING-STATE FMRI ; SEROTONIN TRANSPORTER GENE ; MAJOR DEPRESSIVE DISORDER ; TRACTOGRAPHY-BASED PARCELLATION ; COGNITIVE IMPAIRMENT EVIDENCE ; EARLY ALZHEIMERS-DISEASE ; WHITE-MATTER INTEGRITY ; SMALL-WORLD NETWORKS ; FUNCTIONAL CONNECTIVITY ; ANTIDEPRESSANT RESPONSE |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000322416000020 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/3159 |
专题 | 脑图谱与类脑智能实验室_脑网络组研究 |
作者单位 | 1.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 3.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 610054, Peoples R China 4.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia |
第一作者单位 | 模式识别国家重点实验室 |
推荐引用方式 GB/T 7714 | Jiang, Tianzi. Brainnetome: A new -ome to understand the brain and its disorders[J]. NEUROIMAGE,2013,80:263-272. |
APA | Jiang, Tianzi.(2013).Brainnetome: A new -ome to understand the brain and its disorders.NEUROIMAGE,80,263-272. |
MLA | Jiang, Tianzi."Brainnetome: A new -ome to understand the brain and its disorders".NEUROIMAGE 80(2013):263-272. |
条目包含的文件 | 条目无相关文件。 |
个性服务 |
推荐该条目 |
保存到收藏夹 |
查看访问统计 |
导出为Endnote文件 |
谷歌学术 |
谷歌学术中相似的文章 |
[Jiang, Tianzi]的文章 |
百度学术 |
百度学术中相似的文章 |
[Jiang, Tianzi]的文章 |
必应学术 |
必应学术中相似的文章 |
[Jiang, Tianzi]的文章 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论