Subregions of the human superior frontal gyrus and their connections

	Subregions of the human superior frontal gyrus and their connections
	Li, Wei 1; Qin, Wen 1; Liu, Huaigui 1; Fan, Lingzhong2 ; Wang, Jiaojian 2; Jiang, Tianzi2 ; Yu, Chunshui 1
发表期刊	NEUROIMAGE
	2013-09-01
卷号	78 页码:46-58
文章类型	Article
摘要	The superior frontal gyrus (SFG) is located at the superior part of the prefrontal cortex and is involved in a variety of functions, suggesting the existence of functional subregions. However, parcellation schemes of the human SFG and the connection patterns of each subregion remain unclear. We firstly parcellated the human SFG into the anteromedial (SFGam), dorsolateral (SFGdl), and posterior (SFGp) subregions based on diffusion tensor tractography. The SFGam was anatomically connected with the anterior and mid-cingulate cortices, which are critical nodes of the cognitive control network and the default mode network (DMN). The SFGdl was connected with the middle and inferior frontal gyri, which are involved in the cognitive execution network. The SFGp was connected with the precentral gyrus, caudate, thalamus, and frontal operculum, which are nodes of the motor control network. Resting-state functional connectivity analysis further revealed that the SFGam was mainly correlated with the cognitive control network and the DMN; the SFGdl was correlated with the cognitive execution network and the DMN; and the SFGp was correlated with the sensorimotor-related brain regions. The SFGam and SFGdl were further parcellated into three and two subclusters that are well corresponding to Brodmann areas. These findings suggest that the human SFG consists of multiple dissociable subregions that have distinct connection patterns and that these subregions are involved in different functional networks and serve different functions. These results may improve our understanding on the functional complexity of the SFG and provide us an approach to investigate the SFG at the subregional level. (C) 2013 Elsevier Inc. All rights reserved.
关键词	Diffusion Tensor Imaging Superior Frontal Gyrus Tractography Parcellation Resting-state Fingerprint
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	ANTERIOR CINGULATE CORTEX ; DORSOLATERAL PREFRONTAL CORTEX ; STATE FUNCTIONAL CONNECTIVITY ; DEFAULT MODE NETWORK ; COMPARATIVE CYTOARCHITECTONIC ANALYSIS ; TRANSCRANIAL MAGNETIC STIMULATION ; TRACTOGRAPHY-BASED PARCELLATION ; SUPPLEMENTARY MOTOR AREA ; HUMAN CEREBRAL-CORTEX ; EVENT-RELATED FMRI
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000320488900005
引用统计	被引频次：313[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3160
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.Tianjin Med Univ, Dept Radiol, Gen Hosp, Tianjin 300052, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, LIAMA Ctr Computat Med, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Wei,Qin, Wen,Liu, Huaigui,et al. Subregions of the human superior frontal gyrus and their connections[J]. NEUROIMAGE,2013,78:46-58.
APA	Li, Wei.,Qin, Wen.,Liu, Huaigui.,Fan, Lingzhong.,Wang, Jiaojian.,...&Yu, Chunshui.(2013).Subregions of the human superior frontal gyrus and their connections.NEUROIMAGE,78,46-58.
MLA	Li, Wei,et al."Subregions of the human superior frontal gyrus and their connections".NEUROIMAGE 78(2013):46-58.