Brainnetome-wide association studies in schizophrenia: The advances and future

	Brainnetome-wide association studies in schizophrenia: The advances and future
	Jiang, Tianzi1,2,3,4 ; Zhou, Yuan5,6 ; Liu, Bing1,2 ; Liu, Yong1,2 ; Song, Ming1,2
发表期刊	NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
	2013-12-01
卷号	37 期号:10 页码:2818-2835
文章类型	Review
摘要	Convergent evidence suggests that psychiatric disorders are the result of faulty brain networks. To understand the pathophysiological network mechanisms of psychiatric disorders, it is necessary to integrate multi-level network features obtained using various functional and anatomical brain imaging technologies on different scales. We have proposed a new concept, the brainnetome, to represent this integrative framework. In the present review, we use schizophrenia, a disorder characterized by dysconnectivity, to demonstrate how the brainnetome concept can be applied to the study of psychiatric disorders. We first review studies of abnormal brain networks in schizophrenia that are based on single regions of interest. We then present some advances and challenges in understanding the malfunctions of specific brain networks in schizophrenia. Some recent advances and challenges in understanding abnormal whole brain networks in schizophrenia are also presented. We next briefly introduce a few studies that show how genes related to the risk for schizophrenia affect brain networks. Finally, we present a brief discussion about how the brainnetome concept may influence future research and provide a perspective on challenges in this field. (C) 2013 Elsevier Ltd. All rights reserved.
关键词	Brain Networks Effective Connectivity Functional Connectivity Functional Magnetic Resonance Imaging Schizophrenia
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	DORSOLATERAL PREFRONTAL CORTEX ; AUDITORY VERBAL HALLUCINATIONS ; STATE FUNCTIONAL CONNECTIVITY ; WORKING-MEMORY PERFORMANCE ; SMALL-WORLD NETWORKS ; NAIVE 1ST-EPISODE SCHIZOPHRENIA ; ALTERED EFFECTIVE CONNECTIVITY ; GRAPH-THEORETICAL ANALYSIS ; HUMAN CORTICAL NETWORKS ; TEST-RETEST RELIABILITY
收录类别	SCI
语种	英语
WOS研究方向	Behavioral Sciences ; Neurosciences & Neurology
WOS类目	Behavioral Sciences ; Neurosciences
WOS记录号	WOS:000330490200032
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3170
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 3.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia 4.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 610054, Peoples R China 5.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
第一作者单位	中国科学院自动化研究所; 模式识别国家重点实验室
推荐引用方式 GB/T 7714	Jiang, Tianzi,Zhou, Yuan,Liu, Bing,et al. Brainnetome-wide association studies in schizophrenia: The advances and future[J]. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,2013,37(10):2818-2835.
APA	Jiang, Tianzi,Zhou, Yuan,Liu, Bing,Liu, Yong,&Song, Ming.(2013).Brainnetome-wide association studies in schizophrenia: The advances and future.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS,37(10),2818-2835.
MLA	Jiang, Tianzi,et al."Brainnetome-wide association studies in schizophrenia: The advances and future".NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 37.10(2013):2818-2835.