Anatomical Substrates of the Alerting, Orienting and Executive Control Components of Attention: Focus on the Posterior Parietal Lobe

	Anatomical Substrates of the Alerting, Orienting and Executive Control Components of Attention: Focus on the Posterior Parietal Lobe
	Yin, Xuntao 1,2,3; Zhao, Lu 2; Xu, Junhai 1; Evans, Alan C.2; Fan, Lingzhong4 ; Ge, Haitao 1; Tang, Yuchun 1; Khundrakpam, Budhachandra 2; Wang, Jian 3; Liu, Shuwei 1
发表期刊	PLOS ONE
	2012-11-30
卷号	7 期号:11
文章类型	Article
摘要	Both neuropsychological and functional neuroimaging studies have identified that the posterior parietal lobe (PPL) is critical for the attention function. However, the unique role of distinct parietal cortical subregions and their underlying white matter (WM) remains in question. In this study, we collected both magnetic resonance imaging and diffusion tensor imaging (DTI) data in normal participants, and evaluated their attention performance using attention network test (ANT), which could isolate three different attention components: alerting, orienting and executive control. Cortical thickness, surface area and DTI parameters were extracted from predefined PPL subregions and correlated with behavioural performance. Tract-based spatial statistics (TBSS) was used for the voxel-wise statistical analysis. Results indicated structure-behaviour relationships on multiple levels. First, a link between the cortical thickness and WM integrity of the right inferior parietal regions and orienting performance was observed. Specifically, probabilistic tractography demonstrated that the integrity of WM connectivity between the bilateral inferior parietal lobules mediated the orienting performance. Second, the scores of executive control were significantly associated with the WM diffusion metrics of the right supramarginal gyrus. Finally, TBSS analysis revealed that alerting performance was significant correlated with the fractional anisotropy of local WM connecting the right thalamus and supplementary motor area. We conclude that distinct areas and features within PPL are associated with different components of attention. These findings could yield a more complete understanding of the nature of the PPL contribution to visuospatial attention.
WOS标题词	Science & Technology
关键词[WOS]	LATERAL INTRAPARIETAL AREA ; CORTICAL SURFACE-AREA ; HUMAN CEREBRAL-CORTEX ; EVENT-RELATED FMRI ; SPATIAL ATTENTION ; TOP-DOWN ; VISUAL-ATTENTION ; TARGET DETECTION ; VISUOSPATIAL ATTENTION ; FRONTOPARIETAL NETWORK
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000312376100134
引用统计	被引频次：42[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3179
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.Shandong Univ, Res Ctr Sect & Imaging Anat, Sch Med, Jinan 250100, Shandong, Peoples R China 2.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ, Canada 3.Third Mil Med Univ, Dept Radiol, Southwest Hosp, Chongqing, Peoples R China 4.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Yin, Xuntao,Zhao, Lu,Xu, Junhai,et al. Anatomical Substrates of the Alerting, Orienting and Executive Control Components of Attention: Focus on the Posterior Parietal Lobe[J]. PLOS ONE,2012,7(11).
APA	Yin, Xuntao.,Zhao, Lu.,Xu, Junhai.,Evans, Alan C..,Fan, Lingzhong.,...&Liu, Shuwei.(2012).Anatomical Substrates of the Alerting, Orienting and Executive Control Components of Attention: Focus on the Posterior Parietal Lobe.PLOS ONE,7(11).
MLA	Yin, Xuntao,et al."Anatomical Substrates of the Alerting, Orienting and Executive Control Components of Attention: Focus on the Posterior Parietal Lobe".PLOS ONE 7.11(2012).