CASIA OpenIR  > 脑网络组研究
Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia
Ding, Kun1; Liu, Yong2,3; Yan, Xiaohe1; Lin, Xiaoming1; Jiang, Tianzi2,3,4,5
Source PublicationNEURAL PLASTICITY
2013
SubtypeArticle
AbstractAmblyopia, which usually occurs during early childhood and results in poor or blurred vision, is a disorder of the visual system that is characterized by a deficiency in an otherwise physically normal eye or by a deficiency that is out of proportion with the structural or functional abnormalities of the eye. Our previous study demonstrated alterations in the spontaneous activity patterns of some brain regions in individuals with anisometropic amblyopia compared to subjects with normal vision. To date, it remains unknown whether patients with amblyopia show characteristic alterations in the functional connectivity patterns in the visual areas of the brain, particularly the primary visual area. In the present study, we investigated the differences in the functional connectivity of the primary visual area between individuals with amblyopia and normal-sighted subjects using resting functional magnetic resonance imaging. Our findings demonstrated that the cerebellum and the inferior parietal lobule showed altered functional connectivity with the primary visual area in individuals with amblyopia, and this finding provides further evidence for the disruption of the dorsal visual pathway in amblyopic subjects.
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordLATERAL GENICULATE-NUCLEUS ; TRANSCRANIAL MAGNETIC STIMULATION ; SACCADIC EYE-MOVEMENTS ; ANISOMETROPIC AMBLYOPIA ; GLOBAL MOTION ; POSTERIOR CEREBELLUM ; VISUOMOTOR BEHAVIOR ; PREFRONTAL CORTEX ; DEFICITS ; PERCEPTION
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectNeurosciences
WOS IDWOS:000320802300001
Citation statistics
Cited Times:41[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/3211
Collection脑网络组研究
Affiliation1.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510060, Guangdong, Peoples R China
2.Chinese Acad Sci, Inst Automat, Nat Lab Pattern Recognit, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing 100190, Peoples R China
4.Univ Elect Sci & Technol China, Sch Life Sci & Technol, Minist Educ, Key Lab NeuroInformat, Chengdu 610054, Peoples R China
5.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
Recommended Citation
GB/T 7714
Ding, Kun,Liu, Yong,Yan, Xiaohe,et al. Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia[J]. NEURAL PLASTICITY,2013.
APA Ding, Kun,Liu, Yong,Yan, Xiaohe,Lin, Xiaoming,&Jiang, Tianzi.(2013).Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia.NEURAL PLASTICITY.
MLA Ding, Kun,et al."Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia".NEURAL PLASTICITY (2013).
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