Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging | |
Tian, Jie; Zhong, Jianghong; Qin, Chenghu; Yang, Xin; Zhu, Shuping; Zhang, Xing | |
发表期刊 | International Journal of Biomedical Imaging |
2011 | |
卷号 | 2011期号:2011页码:641618-641618 |
摘要 | Cerenkov luminescence imaging (CLI) is a cost-effective molecular imaging tool for biomedical applications of radiotracers. The introduction of Cerenkov luminescence tomography (CLT) relative to planar CLI can be compared to the development of X-ray CT based on radiography. With CLT, quantitative and localized analysis of a radiopharmaceutical distribution becomes feasible.In this contribution, a feasibility study of in vivo radiopharmaceutical imaging in heterogeneous medium is presented. Coupled with a multimodal in vivo imaging system, this CLT reconstruction method allows precise anatomical registration of the positron probe in heterogeneous tissues and facilitates the more widespread application of radiotracers. Source distribution inside the small animal is obtained from CLT reconstruction. The experimental results demonstrated that CLT can be employed as an available in vivo tomographic imaging of charged particle emitters in a heterogeneous medium. |
关键词 | Radiopharmaceutical Imaging |
收录类别 | EI |
WOS记录号 | WOS:20112514078951 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/3888 |
专题 | 中国科学院分子影像重点实验室 |
通讯作者 | Tian, Jie |
推荐引用方式 GB/T 7714 | Tian, Jie,Zhong, Jianghong,Qin, Chenghu,et al. Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging[J]. International Journal of Biomedical Imaging,2011,2011(2011):641618-641618. |
APA | Tian, Jie,Zhong, Jianghong,Qin, Chenghu,Yang, Xin,Zhu, Shuping,&Zhang, Xing.(2011).Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging.International Journal of Biomedical Imaging,2011(2011),641618-641618. |
MLA | Tian, Jie,et al."Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging".International Journal of Biomedical Imaging 2011.2011(2011):641618-641618. |
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