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Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging
Tian, Jie; Zhong, Jianghong; Qin, Chenghu; Yang, Xin; Zhu, Shuping; Zhang, Xing
发表期刊International Journal of Biomedical Imaging
2011
卷号2011期号:2011页码:641618-641618
摘要Cerenkov luminescence imaging (CLI) is a cost-effective molecular imaging tool for biomedical applications of radiotracers. The introduction of Cerenkov luminescence tomography (CLT) relative to planar CLI can be compared to the development of X-ray
CT based on radiography. With CLT, quantitative and localized analysis of a radiopharmaceutical distribution becomes feasible.In this contribution, a feasibility study of in vivo radiopharmaceutical imaging in heterogeneous medium is presented. Coupled with a multimodal in vivo imaging system, this CLT reconstruction method allows precise anatomical registration of the positron probe in heterogeneous tissues and facilitates the more widespread application of radiotracers. Source distribution inside the small animal is obtained from CLT reconstruction. The experimental results demonstrated that CLT can be employed as an available in vivo tomographic imaging of charged particle emitters in a heterogeneous medium.
关键词Radiopharmaceutical Imaging
收录类别EI
WOS记录号WOS:20112514078951
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/3888
专题中国科学院分子影像重点实验室
通讯作者Tian, Jie
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Tian, Jie,Zhong, Jianghong,Qin, Chenghu,et al. Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging[J]. International Journal of Biomedical Imaging,2011,2011(2011):641618-641618.
APA Tian, Jie,Zhong, Jianghong,Qin, Chenghu,Yang, Xin,Zhu, Shuping,&Zhang, Xing.(2011).Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging.International Journal of Biomedical Imaging,2011(2011),641618-641618.
MLA Tian, Jie,et al."Cerenkov luminescence tomography for in vivo radiopharmaceutical imaging".International Journal of Biomedical Imaging 2011.2011(2011):641618-641618.
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