Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem | |
He, Xiaowei; Liang, Jimin; Qu, Xiaochao; Huang, Heyu; Hou, Yanbin; Tian, Jie | |
发表期刊 | International Journal of Biomedical Imaging |
2010 | |
卷号 | 2010期号:291874页码:11 |
摘要 | In bioluminescence tomography (BLT), reconstruction of internal bioluminescent source distribution from the surface optical signals is an ill-posed inverse problem. In real BLT experiment, apart from the measurement noise, the system errors caused by geometry mismatch, numerical discretization, and optical modeling approximations are also inevitable, which may lead to large errors in the reconstruction results. Most regularization techniques such as Tikhonov method only consider measurement noise, whereas the influences of system errors have not been investigated. In this paper, the truncated total least squares method (TTLS) is introduced into BLT reconstruction, in which both system errors and measurement noise are taken into account. Based on the modified generalized cross validation (MGCV) criterion and residual error minimization, a practical parameter-choice scheme referred to as improved GCV (IGCV) is proposed for TTLS. Numerical simulations with different noise levels and physical experiments demonstrate the effectiveness and potential of TTLS combined with IGCV for solving the BLT inverse problem. |
关键词 | Bioluminescence |
收录类别 | EI |
WOS记录号 | WOS:20102413012832 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/3895 |
专题 | 中国科学院分子影像重点实验室 |
通讯作者 | Tian, Jie |
推荐引用方式 GB/T 7714 | He, Xiaowei,Liang, Jimin,Qu, Xiaochao,et al. Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem[J]. International Journal of Biomedical Imaging,2010,2010(291874):11. |
APA | He, Xiaowei,Liang, Jimin,Qu, Xiaochao,Huang, Heyu,Hou, Yanbin,&Tian, Jie.(2010).Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem.International Journal of Biomedical Imaging,2010(291874),11. |
MLA | He, Xiaowei,et al."Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem".International Journal of Biomedical Imaging 2010.291874(2010):11. |
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