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Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem
He, Xiaowei; Liang, Jimin; Qu, Xiaochao; Huang, Heyu; Hou, Yanbin; Tian, Jie
发表期刊International Journal of Biomedical Imaging
2010
卷号2010期号:291874页码:11
摘要In bioluminescence tomography (BLT), reconstruction of internal bioluminescent source distribution from the surface optical signals is an ill-posed inverse problem. In real BLT experiment, apart from the measurement noise, the system errors caused
by geometry mismatch, numerical discretization, and optical modeling approximations are also inevitable, which may lead to large errors in the reconstruction results. Most regularization techniques such as Tikhonov method only consider measurement
noise, whereas the influences of system errors have not been investigated. In this paper, the truncated total least squares method (TTLS) is introduced into BLT reconstruction, in which both system errors and measurement noise are taken into account. Based on the modified generalized cross validation (MGCV) criterion and residual error minimization, a practical parameter-choice scheme referred to as improved GCV (IGCV) is proposed for TTLS. Numerical simulations with different noise levels and physical experiments demonstrate the effectiveness and potential of TTLS combined with IGCV for solving the BLT inverse problem.
关键词Bioluminescence
收录类别EI
WOS记录号WOS:20102413012832
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/3895
专题中国科学院分子影像重点实验室
通讯作者Tian, Jie
推荐引用方式
GB/T 7714
He, Xiaowei,Liang, Jimin,Qu, Xiaochao,et al. Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem[J]. International Journal of Biomedical Imaging,2010,2010(291874):11.
APA He, Xiaowei,Liang, Jimin,Qu, Xiaochao,Huang, Heyu,Hou, Yanbin,&Tian, Jie.(2010).Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem.International Journal of Biomedical Imaging,2010(291874),11.
MLA He, Xiaowei,et al."Truncated total least squares method with a practical truncation parameter choice scheme for bioluminescence tomography inverse problem".International Journal of Biomedical Imaging 2010.291874(2010):11.
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