Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
A new numerical method for BLT forward problem based on high-order finite elements | |
Hou, Yanbin2; Tian, Jie1,2; Wu, Yan2; Liang, Jimin2; He, Xiaowei2 | |
发表期刊 | COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING |
2009-06-01 | |
卷号 | 25期号:6页码:667-681 |
文章类型 | Article |
摘要 | Molecular imaging possesses the ability to characterize and measure biological processes at the cellular and molecular level in vivo. As one of the new molecular imaging modalities, biolminescence tomography (BLT) is to reconstruct the light distribution inside a small animal from the photon flux measured on its surface. To obtain accurate and robust reconstruction, it needs a good understanding of the propagation of photons in biological tissues, which is referred to as the forward problem in BLT. Because the turbid media is high scattering and low absorption, the propagation process can be described by the steady diffusion equation. In this paper, an hp-adaptivity method for BLT forward problem is presented based on finite elements of high orders and moderate meshes by finite element method (FEM). Both numerical simulation and physical experiment are performed to evaluate the accuracy of solution and the efficiency of computation. The relevant results show that element order is more critical than mesh size to produce an accurate FEM solution efficiently. Copyright (C) 2008 John Wiley & Sons, Ltd. |
关键词 | Molecular Imaging Bioluminescence Tomography Forward Problem High-order Finite Elements Diffusion Approximation |
WOS标题词 | Science & Technology ; Technology ; Physical Sciences |
关键词[WOS] | BIOLUMINESCENCE TOMOGRAPHY ; SCATTERING MEDIA ; IN-VIVO ; LIGHT ; TRANSPORT ; RECONSTRUCTION ; PROPAGATION ; SIMULATION |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Engineering ; Mathematics |
WOS类目 | Engineering, Multidisciplinary ; Mathematics, Interdisciplinary Applications |
WOS记录号 | WOS:000267062200007 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/3904 |
专题 | 中国科学院分子影像重点实验室 |
通讯作者 | Tian, Jie |
作者单位 | 1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China 2.Xidian Univ, Sch Elect Engn, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China |
通讯作者单位 | 中国科学院自动化研究所 |
推荐引用方式 GB/T 7714 | Hou, Yanbin,Tian, Jie,Wu, Yan,et al. A new numerical method for BLT forward problem based on high-order finite elements[J]. COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,2009,25(6):667-681. |
APA | Hou, Yanbin,Tian, Jie,Wu, Yan,Liang, Jimin,&He, Xiaowei.(2009).A new numerical method for BLT forward problem based on high-order finite elements.COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,25(6),667-681. |
MLA | Hou, Yanbin,et al."A new numerical method for BLT forward problem based on high-order finite elements".COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING 25.6(2009):667-681. |
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文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
173.Communications i(409KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 |
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