A new numerical method for BLT forward problem based on high-order finite elements

	A new numerical method for BLT forward problem based on high-order finite elements
	Hou, Yanbin 2; Tian, Jie 1,2; Wu, Yan 2; Liang, Jimin 2; He, Xiaowei 2
发表期刊	COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING
	2009-06-01
卷号	25 期号:6 页码:667-681
文章类型	Article
摘要	Molecular imaging possesses the ability to characterize and measure biological processes at the cellular and molecular level in vivo. As one of the new molecular imaging modalities, biolminescence tomography (BLT) is to reconstruct the light distribution inside a small animal from the photon flux measured on its surface. To obtain accurate and robust reconstruction, it needs a good understanding of the propagation of photons in biological tissues, which is referred to as the forward problem in BLT. Because the turbid media is high scattering and low absorption, the propagation process can be described by the steady diffusion equation. In this paper, an hp-adaptivity method for BLT forward problem is presented based on finite elements of high orders and moderate meshes by finite element method (FEM). Both numerical simulation and physical experiment are performed to evaluate the accuracy of solution and the efficiency of computation. The relevant results show that element order is more critical than mesh size to produce an accurate FEM solution efficiently. Copyright (C) 2008 John Wiley & Sons, Ltd.
关键词	Molecular Imaging Bioluminescence Tomography Forward Problem High-order Finite Elements Diffusion Approximation
WOS标题词	Science & Technology ; Technology ; Physical Sciences
关键词[WOS]	BIOLUMINESCENCE TOMOGRAPHY ; SCATTERING MEDIA ; IN-VIVO ; LIGHT ; TRANSPORT ; RECONSTRUCTION ; PROPAGATION ; SIMULATION
收录类别	SCI
语种	英语
WOS研究方向	Engineering ; Mathematics
WOS类目	Engineering, Multidisciplinary ; Mathematics, Interdisciplinary Applications
WOS记录号	WOS:000267062200007
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3904
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China 2.Xidian Univ, Sch Elect Engn, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Hou, Yanbin,Tian, Jie,Wu, Yan,et al. A new numerical method for BLT forward problem based on high-order finite elements[J]. COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,2009,25(6):667-681.
APA	Hou, Yanbin,Tian, Jie,Wu, Yan,Liang, Jimin,&He, Xiaowei.(2009).A new numerical method for BLT forward problem based on high-order finite elements.COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING,25(6),667-681.
MLA	Hou, Yanbin,et al."A new numerical method for BLT forward problem based on high-order finite elements".COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING 25.6(2009):667-681.

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