Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography | |
| Han, Runqiang1,2; Liang, Jimin1; Qu, Xiaochao1; Hou, Yanbin1; Ren, Nunu1,2; Mao, Jingjing1,2; Tian, Jie1,2,3 | |
| 发表期刊 | OPTICS EXPRESS
 |
| 2009-08-17 | |
| 卷号 | 17期号:17页码:14481-14494 |
| 文章类型 | Article |
| 摘要 | As a novel modality of molecular imaging, bioluminescence tomography (BLT) is used to in vivo observe and measure the biological process at cellular and molecular level in small animals. The core issue of BLT is to determine the distribution of internal bioluminescent sources from optical measurements on external surface. In this paper, a new algorithm is presented for BLT source reconstruction based on adaptive hp-finite element method. Using adaptive mesh refinement strategy and intelligent permissible source region, we can obtain more accurate information about the location and density of sources, with the robustness, stability and efficiency improved. Numerical simulations and physical experiment were both conducted to verify the performance of the proposed algorithm, where the optical data on phantom surface were obtained via Monte Carlo simulation and CCD camera detection, respectively. The results represent the merits and potential of our algorithm for BLT source reconstruction. (C) 2009 Optical Society of America |
| 关键词 | Tomography Image Reconstruction Techniques Spectroscopy Fluorescence Luminescence |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 关键词[WOS] | FINITE-ELEMENT-METHOD ; OPTICAL-PROPERTIES ; APPROXIMATION ; LIGHT ; INFORMATION ; STRATEGY ; MEDIA |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Optics |
| WOS类目 | Optics |
| WOS记录号 | WOS:000269232800003 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ia.ac.cn/handle/173211/3905 |
| 专题 | 中国科学院分子影像重点实验室 |
| 通讯作者 | Tian, Jie |
| 作者单位 | 1.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 2.Xidian Univ, Sch Elect Engn, Xian 710071, Shaanxi, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
| 通讯作者单位 | 中国科学院自动化研究所 |
| 推荐引用方式 GB/T 7714 | Han, Runqiang,Liang, Jimin,Qu, Xiaochao,et al. A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography[J]. OPTICS EXPRESS,2009,17(17):14481-14494. |
| APA | Han, Runqiang.,Liang, Jimin.,Qu, Xiaochao.,Hou, Yanbin.,Ren, Nunu.,...&Tian, Jie.(2009).A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography.OPTICS EXPRESS,17(17),14481-14494. |
| MLA | Han, Runqiang,et al."A source reconstruction algorithm based on adaptive hp-FEM for bioluminescence tomography".OPTICS EXPRESS 17.17(2009):14481-14494. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 32.OE(2009).pdf（1084KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 | |
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