Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient

	Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient
	Liu, Jiangang 6; Wang, Meiyun 7; Shi, Xiaohong 7; Feng, Lu 8; Li, Ling6 ; Thacker, Justine Marie 10; Tian, Jie 8,9; Shi, Dapeng 7; Lee, Kang 10
发表期刊	CEREBRAL CORTEX
	2014-08-01
卷号	24 期号:8 页码:2081-2092
文章类型	Article
摘要	Brains can perceive or recognize a face even though we are subjectively unaware of the existence of that face. However, the exact neural correlates of such covert face processing remain unknown. Here, we compared the fMRI activities between a prosopagnosic patient and normal controls when they saw famous and unfamiliar faces. When compared with objects, the patient showed greater activation to famous faces in the fusiform face area (FFA) though he could not overtly recognize those faces. In contrast, the controls showed greater activation to both famous and unfamiliar faces in the FFA. Compared with unfamiliar faces, famous faces activated the controls', but not the patient's lateral prefrontal cortex (LPFC) known to be involved in familiar face recognition. In contrast, the patient showed greater activation in the bilateral medial frontal gyrus (MeFG). Functional connectivity analyses revealed that the patient's right middle fusiform gyrus (FG) showed enhanced connectivity to the MeFG, whereas the controls' middle FG showed enhanced connectivity to the LPFC. These findings suggest that the FFA may be involved in both covert and overt face recognition. The patient's impairment in overt face recognition may be due to the absence of the coupling between the right FG and the LPFC.
关键词	Fmri Face Processing Fusiform Gyrus Prosopagnosia Covert Recognition
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	DISTRIBUTED CORTICAL NETWORK ; FUSIFORM GYRUS ; RECOGNITION ; PERCEPTION ; BRAIN ; AREA ; MEMORY ; LOBE ; DISSOCIATION ; INFORMATION
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000340068500010
引用统计	被引频次：10[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3995
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China 2.Henan Prov Peoples Hosp, Zhengzhou 450003, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 4.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Peoples R China 5.Univ Toronto, Dr Eric Jackman Inst Child Study, Toronto, ON M5R 2X2, Canada 6.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China 7.Henan Prov Peoples Hosp, Zhengzhou 450003, Peoples R China 8.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 9.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Peoples R China 10.Univ Toronto, Dr Eric Jackman Inst Child Study, Toronto, ON M5R 2X2, Canada
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Liu, Jiangang,Wang, Meiyun,Shi, Xiaohong,et al. Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient[J]. CEREBRAL CORTEX,2014,24(8):2081-2092.
APA	Liu, Jiangang.,Wang, Meiyun.,Shi, Xiaohong.,Feng, Lu.,Li, Ling.,...&Lee, Kang.(2014).Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient.CEREBRAL CORTEX,24(8),2081-2092.
MLA	Liu, Jiangang,et al."Neural Correlates of Covert Face Processing: fMRI Evidence from a Prosopagnosic Patient".CEREBRAL CORTEX 24.8(2014):2081-2092.

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