Expertise modulates local regional homogeneity of spontaneous brain activity in the resting brain: An fMRI study using the model of skilled acupuncturists

	Expertise modulates local regional homogeneity of spontaneous brain activity in the resting brain: An fMRI study using the model of skilled acupuncturists
	Dong, Minghao 1; Qin, Wei 1; Zhao, Ling 2; Yang, Xuejuan 1; Yuan, Kai 1; Zeng, Fang 2; Sun, Jinbo 1; Yu, Dahua 1; von Deneen, Karen M.1; Liang, Fanrong 2; Tian, Jie 1,3
发表期刊	HUMAN BRAIN MAPPING
	2014-03-01
卷号	35 期号:3 页码:1074-1084
文章类型	Article
摘要	Studies on training/expertise-related effects on human brain in context of neuroplasticity have revealed that plastic changes modulate not only task activations but also patterns and strength of internetworks and intranetworks functional connectivity in the resting state. Much has known about plastic changes in resting state on global level; however, how training/expertise-related effect affects patterns of local spontaneous activity in resting brain remains elusive. We investigated the homogeneity of local blood oxygen level-dependent fluctuations in the resting state using a regional homogeneity (ReHo) analysis among 16 acupuncturists and 16 matched nonacupuncturists (NA). To prove acupuncturists' expertise, we used a series of psychophysical tests. Our results demonstrated that, acupuncturists significantly outperformed NA in tactile-motor and emotional regulation domain and the acupuncturist group showed increased coherence in local BOLD signal fluctuations in the left primary motor cortex (MI), the left primary somatosensory cortex (SI) and the left ventral medial prefrontal cortex/orbitofrontal cortex (VMPFC/OFC). Regression analysis displayed that, in the acupuncturists group, ReHo of VMPFC/OFC could predict behavioral outcomes, evidenced by negative correlation between unpleasantness ratings and ReHo of VMPFC/OFC and ReHo of SI and MI positively correlated with the duration of acupuncture practice. We suggest that expertise could modulate patterns of local resting state activity by increasing regional clustering strength, which is likely to contribute to advanced local information processing efficiency. Our study completes the understanding of neuroplasticity changes by adding the evidence of local resting state activity alterations, which is helpful for elucidating in what manner training effect extends beyond resting state. Hum Brain Mapp 35:1074-1084, 2014. (c) 2013 Wiley Periodicals, Inc.
关键词	Expertise-related Functional Plasticity Regional Homogeneity Resting State Functional Mri Local Modulation Acupuncturist
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	TACTILE DISCRIMINATION ; FUNCTIONAL ACTIVATION ; GRATING ORIENTATION ; STRUCTURAL-CHANGES ; MOTOR CORTEX ; GRAY-MATTER ; PLASTICITY ; NETWORKS ; EMOTION ; TASK
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000334398500026
引用统计	被引频次：25[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3996
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Dong, Minghao,Qin, Wei,Zhao, Ling,et al. Expertise modulates local regional homogeneity of spontaneous brain activity in the resting brain: An fMRI study using the model of skilled acupuncturists[J]. HUMAN BRAIN MAPPING,2014,35(3):1074-1084.
APA	Dong, Minghao.,Qin, Wei.,Zhao, Ling.,Yang, Xuejuan.,Yuan, Kai.,...&Tian, Jie.(2014).Expertise modulates local regional homogeneity of spontaneous brain activity in the resting brain: An fMRI study using the model of skilled acupuncturists.HUMAN BRAIN MAPPING,35(3),1074-1084.
MLA	Dong, Minghao,et al."Expertise modulates local regional homogeneity of spontaneous brain activity in the resting brain: An fMRI study using the model of skilled acupuncturists".HUMAN BRAIN MAPPING 35.3(2014):1074-1084.

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