Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG

	Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG
	You, Youbo 1; Bai, Lijun 1; Dai, Ruwei1 ; Cheng, Hao 3; Liu, Zhenyu1 ; Wei, Wenjuan 1; Tian, Jie 1,2
发表期刊	PLOS ONE
	2013-05-17
卷号	8 期号:5 页码:-
文章类型	Article
摘要	Acupuncture, an externally somatosensory stimulation in the Traditional Chinese Medicine, has been proposed about its modulations on the brain's default mode network (DMN). However, it is still unknown on how the internal brain resting networks are modulated and what inferences can be made about the physiological processes underlying these changes. Combining high spatial resolution of functional magnetic resonance imaging (fMRI) with high temporal resolution of magnetoencephalography (MEG), in the current multimodal study, we sought to explore spatiotemporally whether or not band- specific DMN hub configurations would be induced by verum acupuncture, compared with sham control. Spatial independent component analysis was applied to fMRI data, followed by the discrete regional sources seeded into MEG data. Partial correlation analysis was further adopted to estimate the intrinsic functional connectivity and network hub configurations. One of the most striking findings is that the posterior cingulate cortex is not only validated as a robust DMN hub, but served as a hub only within the delta and gamma bands following the verum acupuncture, compared with its consistently being a DMN hub in sham control group. Our preliminary results may provide a new perspective to lend support for the specificity of neural mechanism underlying acupuncture.
关键词	Combining Fmri Meg
WOS标题词	Science & Technology
关键词[WOS]	RANDOMIZED CONTROLLED-TRIAL ; FUNCTIONAL MRI DATA ; GRAPH-THEORETICAL ANALYSIS ; HUMAN BRAIN ACTIVITY ; ALZHEIMERS-DISEASE ; CONNECTIVITY PATTERNS ; TEMPORAL CORRELATIONS ; HEALTHY-SUBJECTS ; CORTEX ; MODULATION
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000319107900105
引用统计	被引频次：22[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4006
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging & Funct Imaging, Beijing, Peoples R China 2.Xidian Univ, Sch Elect Engn, Life Sci Res Ctr, Xian, Saarbrucken, Peoples R China 3.Capital Med Univ, Beijing Ditan Hosp, Dept Anesthesiol, Beijing, Peoples R China
第一作者单位	中国科学院自动化研究所
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	You, Youbo,Bai, Lijun,Dai, Ruwei,et al. Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG[J]. PLOS ONE,2013,8(5):-.
APA	You, Youbo.,Bai, Lijun.,Dai, Ruwei.,Cheng, Hao.,Liu, Zhenyu.,...&Tian, Jie.(2013).Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG.PLOS ONE,8(5),-.
MLA	You, Youbo,et al."Altered Hub Configurations within Default Mode Network following Acupuncture at ST36: A Multimodal Investigation Combining fMRI and MEG".PLOS ONE 8.5(2013):-.

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