Robust Tract Skeleton Extraction of Cingulum Based on Active Contour Model from Diffusion Tensor MR Imaging

	Robust Tract Skeleton Extraction of Cingulum Based on Active Contour Model from Diffusion Tensor MR Imaging
	Li, Wu1,2,3 ; Hu, Xiaoping2,3
发表期刊	PLOS ONE
	2013-02-26
卷号	8 期号:2 页码:-
文章类型	Article
摘要	Cingulum is widely studied in healthy and psychiatric subjects. For cingulum analysis from diffusion tensor MR imaging, tractography and tract of interest method have been adopted for tract-based analysis. Because tractography performs fiber tracking according to local diffusion measures, they can be sensitive to noise and tracking errors can be accumulated along the fiber. For more accurate localization of cingulum, we attempt to define it by skeleton extraction using the tensors' information throughout the tract of cingulum simultaneously, which is quite different from the idea of tractography. In this study, we introduce an approach to extract the skeleton of cingulum using active contour model, which allows us to optimize the location of cingulum in a global sense based on the diffusion measurements along the entire tract and contour regularity. Validation of this method on synthetic and experimental data proved that our approach is able to reduce the influence of noise and partial volume effect, and extract the skeleton of cingulum robustly and reliably. Our proposed method provides an approach to localize cingulum robustly, which is a very important feature for tract-based analysis and can be of important practical utility.
WOS标题词	Science & Technology
关键词[WOS]	WHITE-MATTER ; HUMAN BRAIN ; TRACTOGRAPHY ; TRACKING ; SEGMENTATION ; CONNECTIVITY ; DEFLECTION ; CORTEX
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000315561400007
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4010
专题	中国科学院分子影像重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Management & Control Complex Syst, Inst Automat, Beijing, Peoples R China 2.Georgia Tech, Dept Biomed Engn, Atlanta, GA USA 3.Emory Univ, Atlanta, GA 30322 USA
第一作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Li, Wu,Hu, Xiaoping. Robust Tract Skeleton Extraction of Cingulum Based on Active Contour Model from Diffusion Tensor MR Imaging[J]. PLOS ONE,2013,8(2):-.
APA	Li, Wu,&Hu, Xiaoping.(2013).Robust Tract Skeleton Extraction of Cingulum Based on Active Contour Model from Diffusion Tensor MR Imaging.PLOS ONE,8(2),-.
MLA	Li, Wu,et al."Robust Tract Skeleton Extraction of Cingulum Based on Active Contour Model from Diffusion Tensor MR Imaging".PLOS ONE 8.2(2013):-.