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Total variation regularization for bioluminescence tomography with the split Bregman method
Feng, Jinchao1; Qin, Chenghu2; Jia, Kebin1; Zhu, Shouping3; Liu, Kai2; Han, Dong2; Yang, Xin2; Gao, Quansheng3; Tian, Jie2,4
Source PublicationAPPLIED OPTICS
2012-07-01
Volume51Issue:19Pages:4501-4512
SubtypeArticle
AbstractRegularization methods have been broadly applied to bioluminescence tomography (BLT) to obtain stable solutions, including l(2) and l(1) regularizations. However, l(2) regularization can oversmooth reconstructed images and l(1) regularization may sparsify the source distribution, which degrades image quality. In this paper, the use of total variation (TV) regularization in BLT is investigated. Since a nonnegativity constraint can lead to improved image quality, the nonnegative constraint should be considered in BLT. However, TV regularization with a nonnegativity constraint is extremely difficult to solve due to its nondifferentiability and nonlinearity. The aim of this work is to validate the split Bregman method to minimize the TV regularization problem with a nonnegativity constraint for BLT. The performance of split Bregman-resolved TV (SBRTV) based BLT reconstruction algorithm was verified with numerical and in vivo experiments. Experimental results demonstrate that the SBRTV regularization can provide better regularization quality over l(2) and l(1) regularizations. (c) 2012 Optical Society of America
KeywordOrthogonal Experimental Design Chemical Substitution Yag:Ce
WOS HeadingsScience & Technology ; Physical Sciences
WOS KeywordTOTAL-VARIATION MINIMIZATION ; IMAGE-RECONSTRUCTION ; OPTICAL TOMOGRAPHY ; SIMULATION ; ALGORITHMS ; STRATEGY
Indexed BySCI
Language英语
WOS Research AreaOptics
WOS SubjectOptics
WOS IDWOS:000306100100029
Citation statistics
Cited Times:25[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/4029
Collection中国科学院分子影像重点实验室
Corresponding AuthorJia, Kebin
Affiliation1.Beijing Univ Technol, Coll Elect Informat & Control Engn, Beijing 100124, Peoples R China
2.Chinese Acad Sci, Inst Automat, Intelligent Med Res Ctr, Beijing 100190, Peoples R China
3.Acad Mil Med Sci, Lab Anim Ctr, Beijing 100850, Peoples R China
4.Xidian Univ, Life Sci Res Ctr, Xian 710071, Peoples R China
Recommended Citation
GB/T 7714
Feng, Jinchao,Qin, Chenghu,Jia, Kebin,et al. Total variation regularization for bioluminescence tomography with the split Bregman method[J]. APPLIED OPTICS,2012,51(19):4501-4512.
APA Feng, Jinchao.,Qin, Chenghu.,Jia, Kebin.,Zhu, Shouping.,Liu, Kai.,...&Tian, Jie.(2012).Total variation regularization for bioluminescence tomography with the split Bregman method.APPLIED OPTICS,51(19),4501-4512.
MLA Feng, Jinchao,et al."Total variation regularization for bioluminescence tomography with the split Bregman method".APPLIED OPTICS 51.19(2012):4501-4512.
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