Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| Comparative studies of l(p)-regularization-based reconstruction algorithms for bioluminescence tomography | |
| Zhang, Qitan1; Chen, Xueli1; Qu, Xiaochao1; Liang, Jimin1; Tian, Jie1,2 | |
| 发表期刊 | BIOMEDICAL OPTICS EXPRESS
 |
| 2012-11-01 | |
| 卷号 | 3期号:11页码:2916-2936 |
| 文章类型 | Article |
| 摘要 | Inverse source reconstruction is the most challenging aspect of bioluminescence tomography (BLT) because of its ill-posedness. Although many efforts have been devoted to this problem, so far, there is no generally accepted method. Due to the ill-posedness property of the BLT inverse problem, the regularization method plays an important role in the inverse reconstruction. In this paper, six reconstruction algorithms based on l(p) regularization are surveyed. The effects of the permissible source region, measurement noise, optical properties, tissue specificity and source locations on the performance of the reconstruction algorithms are investigated using a series of single source experiments. In order to further inspect the performance of the reconstruction algorithms, we present the double sources and the in vivo mouse experiments to study their resolution ability and potential for a practical heterogeneous mouse experiment. It is hoped to provide useful guidance on algorithm development and application in the related fields. (C) 2012 Optical Society of America |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 关键词[WOS] | OPTICAL TOMOGRAPHY ; MODEL ; REGULARIZATION ; EQUATIONS ; MOUSE ; LIGHT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS类目 | Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS记录号 | WOS:000310644700022 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ia.ac.cn/handle/173211/4038 |
| 专题 | 中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 2.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Qitan,Chen, Xueli,Qu, Xiaochao,et al. Comparative studies of l(p)-regularization-based reconstruction algorithms for bioluminescence tomography[J]. BIOMEDICAL OPTICS EXPRESS,2012,3(11):2916-2936. |
| APA | Zhang, Qitan,Chen, Xueli,Qu, Xiaochao,Liang, Jimin,&Tian, Jie.(2012).Comparative studies of l(p)-regularization-based reconstruction algorithms for bioluminescence tomography.BIOMEDICAL OPTICS EXPRESS,3(11),2916-2936. |
| MLA | Zhang, Qitan,et al."Comparative studies of l(p)-regularization-based reconstruction algorithms for bioluminescence tomography".BIOMEDICAL OPTICS EXPRESS 3.11(2012):2916-2936. |
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| 40.BOE(2012).pdf（5003KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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