Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study

	Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study
	Sun, Jinbo 1; Zhu, Yuanqiang 1; Jin, Lingmin 1; Yang, Yang 1; von Deneen, KarenM.1; Qin, Wei 1; Gong, Qiyong 2; Tian, Jie 1,3
发表期刊	EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
	2012
卷号	27 期号:9 页码:2349-2356
文章类型	Article
摘要	Nowadays, functional magnetic resonance imaging (fMRI) has become one of the most important ways to explore the central mechanism of acupuncture. Among these studies, activations around the somatosensory-related brain network had the most robust blood oxygen level-dependent (BOLD) responses. However, due to the insufficient control of the subjective sensations during acupuncture stimulation, whether these robust activations reflected the pattern of de-qi, sharp pain, or mixed (de-qi + sharp pain) sensations was largely unknown. The current study recruited 50 subjects and grouped them into two groups according to whether he/she experienced sharp pain during acupuncture stimulation to give a definite answer to the aforesaid question. Our results indicated that BOLD responses associated with de-qi during acupuncture stimulation at ST36 were activation dominated. Furthermore, both the quantitative and qualitative differences of BOLD responses between de-qi and mixed sensations evoked by acupuncture stimulation were significant. The pattern of BOLD responses of sharp pain might be partly separated from that of de-qi in the spatial distribution. Therefore, we proposed that in order to explore the specific central mechanism of acupuncture, subjects with sharp pain should be excluded from those with only de-qi.
关键词	Distribution Between De-qi
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	EVOKED-POTENTIALS ; FUNCTIONAL MRI ; GLOBAL SIGNAL ; ELECTROACUPUNCTURE STIMULATION ; ELECTRICAL-STIMULATION ; CORTICAL NETWORK ; BRAIN ACTIVITY ; LIMBIC SYSTEM ; MUSCLE PAIN ; SKIN
收录类别	SCI
语种	英语
WOS研究方向	Integrative & Complementary Medicine
WOS类目	Integrative & Complementary Medicine
WOS记录号	WOS:000313191200001
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4054
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Xidian Univ, Sch Life Sci & Technol, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China 2.Sichuan Univ, W China Hosp, Dept Radiol, Huaxi MR Res Ctr HMRRC,Ctr Med Imaging, Chengdu 610041, Sichuan, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Sun, Jinbo,Zhu, Yuanqiang,Jin, Lingmin,et al. Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2012,27(9):2349-2356.
APA	Sun, Jinbo.,Zhu, Yuanqiang.,Jin, Lingmin.,Yang, Yang.,von Deneen, KarenM..,...&Tian, Jie.(2012).Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,27(9),2349-2356.
MLA	Sun, Jinbo,et al."Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 27.9(2012):2349-2356.

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