CASIA OpenIR  > 中国科学院分子影像重点实验室
Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization
Wu, Ping1; Hu, Yifang2; Wang, Kun1; Tian, Jie1
Source PublicationIEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
2014
Volume61Issue:1Pages:189-196
SubtypeArticle
AbstractBioluminescence tomography is a promising tool in preclinical research, enabling noninvasive real-time in vivo imaging as well as quantitative analysis in small animal studies. Due to the difficulty of reconstruction, continuous efforts are still made to find more practical and efficient approaches. In this paper, we present an iterative reweighted l(2)-norm optimization incorporating anatomical structures in order to enhance the performance of bioluminescence tomography. The structure priors have been utilized to generate a heterogeneous mouse model by extracting the internal organs and tissues, which can assist in establishing a more precise photon diffusion model, as well as reflecting a more specific position of the reconstruction results inside the mouse. To evaluate the performance of the iterative reweighted approach, several numerical simulation studies including comparative analyses and multisource cases have been conducted to reconstruct the same datasets. The results suggest that the proposed method is able to ensure the accuracy, robustness, and efficiency of bioluminescence tomography. Finally, an in vivo experiment was performed to further validate its feasibility in a practical application.
KeywordBioluminescence Tomography Hybrid Imaging Optical Molecular Imaging (Omi) 3-d Reconstruction
WOS HeadingsScience & Technology ; Technology
WOS KeywordIMAGE-RECONSTRUCTION ; OPTICAL TOMOGRAPHY ; IN-VIVO ; SHEDDING LIGHT ; LIMITED DATA ; ALGORITHM ; CANCER ; MODEL
Indexed BySCI
Language英语
WOS Research AreaEngineering
WOS SubjectEngineering, Biomedical
WOS IDWOS:000333263300020
Citation statistics
Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/4060
Collection中国科学院分子影像重点实验室
Corresponding AuthorTian, Jie
Affiliation1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging & Funct Imaging, Beijing 100190, Peoples R China
2.Beijing Jiaotong Univ, Dept Biomed Engn, Sch Comp & Informat Technol, Beijing 100044, Peoples R China
First Author AffilicationInstitute of Automation, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Automation, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wu, Ping,Hu, Yifang,Wang, Kun,et al. Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING,2014,61(1):189-196.
APA Wu, Ping,Hu, Yifang,Wang, Kun,&Tian, Jie.(2014).Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization.IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING,61(1),189-196.
MLA Wu, Ping,et al."Bioluminescence Tomography by an Iterative Reweighted l(2)-Norm Optimization".IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING 61.1(2014):189-196.
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