Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| Alterations of regional spontaneous neuronal activity and corresponding brain circuit changes during resting state in migraine without aura | |
Xue, Ting1; Yuan, Kai1; Cheng, Ping1; Zhao, Ling2; Zhao, Limei1; Yu, Dahua1,3; Dong, Tao1; von Deneen, Karen M.1; Gong, Qiyong4; Qin, Wei1; Tian, Jie1,5
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| Source Publication | NMR IN BIOMEDICINE
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| 2013-09-01 | |
| Volume | 26Issue:9Pages:1051-1058 |
| Subtype | Article |
| Abstract | Although previous resting-state studies have reported abnormal functional cerebral changes in patients with migraine without aura (MwoA), few have focused on alterations in both regional spontaneous neuronal activity and corresponding brain circuits in MwoA patients during rest. Eighteen MwoA patients and 18 age- and gender-matched healthy controls (HC) were recruited in the current study. Baseline cerebral alterations were investigated using amplitude of low-frequency fluctuation (ALFF) and region of interest (ROI)-based functional connectivity (FC) analyses. Compared with HC, MwoA patients showed decreased ALFF values in the left rostral anterior cingulate cortex (rACC) and bilateral prefrontal cortex (PFC) as well as increased ALFF values in the right thalamus. FC analysis also revealed abnormal FCs associated with these ROIs. In addition, ALFF values of the left rACC correlated with duration of disease in MwoA. Our findings could lead to a better understanding of intrinsic functional architecture of baseline brain activity in MwoA, providing both regional and brain circuit spontaneous neuronal activity properties. Copyright (c) 2013 John Wiley & Sons, Ltd. |
| Keyword | Migraine Without Aura (Mwoa) Amplitude Of Low-frequency Fluctuation (Alff) Functional Connectivity (Fc) Resting State Functional Magnetic Resonance Imaging (Fmri) |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| WOS Keyword | FUNCTIONAL MAGNETIC-RESONANCE ; HEROIN-DEPENDENT INDIVIDUALS ; PERIAQUEDUCTAL GRAY-MATTER ; LOW-FREQUENCY FLUCTUATION ; VOXEL-BASED MORPHOMETRY ; DEFAULT-MODE NETWORK ; ALZHEIMERS-DISEASE ; ANTERIOR CINGULATE ; STEM ACTIVATION ; CEREBRAL-CORTEX |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy |
| WOS Subject | Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy |
| WOS ID | WOS:000323078700001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ia.ac.cn/handle/173211/4095 |
| Collection | 中国科学院分子影像重点实验室 |
| Corresponding Author | Tian, Jie |
| Affiliation | 1.Xidian Univ, Sch Life Sci & Technol, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu 610075, Sichuan, Peoples R China 3.Inner Mongolia Univ Sci & Technol, Sch Informat Engn, Informat Proc Lab, Baotou 014010, Inner Mongolia, Peoples R China 4.Sichuan Univ, West China Hosp, Ctr Diagnost Imaging, Dept Radiol,Huaxi MR Res Ctr HMRRC, Chengdu, Peoples R China 5.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
| Corresponding Author Affilication | Institute of Automation, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Xue, Ting,Yuan, Kai,Cheng, Ping,et al. Alterations of regional spontaneous neuronal activity and corresponding brain circuit changes during resting state in migraine without aura[J]. NMR IN BIOMEDICINE,2013,26(9):1051-1058. |
| APA | Xue, Ting.,Yuan, Kai.,Cheng, Ping.,Zhao, Ling.,Zhao, Limei.,...&Tian, Jie.(2013).Alterations of regional spontaneous neuronal activity and corresponding brain circuit changes during resting state in migraine without aura.NMR IN BIOMEDICINE,26(9),1051-1058. |
| MLA | Xue, Ting,et al."Alterations of regional spontaneous neuronal activity and corresponding brain circuit changes during resting state in migraine without aura".NMR IN BIOMEDICINE 26.9(2013):1051-1058. |
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| 84.NMR in Biomedicin（325KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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