Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study

	Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study
	Yu, Dahua 1,2; Yuan, Kai 1; Zhao, Ling 3; Zhao, Limei 1; Dong, Minghao 1; Liu, Peng 1; Wang, Guihong 1,4; Liu, Jixin 1; Sun, Jinbo 1; Zhou, Guangyu 1; von Deneen, Karen M.1; Liang, Fanrong 3; Qin, Wei 1; Tian, Jie 1,5
发表期刊	NMR IN BIOMEDICINE
	2012-05-01
卷号	25 期号:5 页码:806-812
文章类型	Article
摘要	Previous studies have provided evidence of structural and task-related functional changes in the brains of patients with migraine without aura. Resting-state brain activity in patients with migraine provides clues to the pathophysiology of the disease. However, few studies have focused on the resting-state abnormalities in patients with migraine without aura. In the current study, we employed a data-driven method, regional homogeneity (ReHo), to analyze the local features of spontaneous brain activity in patients with migraine without aura during the resting state. Twenty-six patients with migraine without aura and 26 age-, education- and gender-matched healthy volunteers participated in this study. Compared with healthy controls, patients with migraine without aura showed a significant decrease in ReHo values in the right rostral anterior cingulate cortex (rACC), the prefrontal cortex (PFC), the orbitofrontal cortex (OFC) and the supplementary motor area (SMA). In addition, we found that ReHo values were negatively correlated with the duration of disease in the right rACC and PFC. Our results suggest that the resting-state abnormalities of these regions may be associated with functional impairments in pain processing in patients with migraine without aura. We hope that our results will improve the understanding of migraine. Copyright (C) 2011 John Wiley & Sons, Ltd.
关键词	Migraine Without Aura Regional Homogeneity (Reho) Resting State Functional Mri (fMri) Supplementary Motor Area (Sma) Prefrontal Cortex (Pfc) Rostral Anterior Cingulate Cortex (Racc) Orbitofrontal Cortex (Ofc)
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology
关键词[WOS]	HEROIN-DEPENDENT INDIVIDUALS ; MEDIAL FRONTAL-CORTEX ; HUMAN ORBITOFRONTAL CORTEX ; VOXEL-BASED MORPHOMETRY ; GREY-MATTER CHANGES ; HUMAN BRAIN ; PAIN PERCEPTION ; GRAY-MATTER ; FUNCTIONAL CONNECTIVITY ; NEURAL ACTIVITY
收录类别	SCI
语种	英语
WOS研究方向	Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy
WOS类目	Biophysics ; Radiology, Nuclear Medicine & Medical Imaging ; Spectroscopy
WOS记录号	WOS:000302617600012
引用统计	被引频次：88[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4101
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 2.Inner Mongolia Univ Sci & Technol, Informat Proc Lab, Sch Informat Engn, Baotou, Inner Mongolia, Peoples R China 3.Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China 4.Xidian Univ, Dept Appl Math, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 5.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Yu, Dahua,Yuan, Kai,Zhao, Ling,et al. Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study[J]. NMR IN BIOMEDICINE,2012,25(5):806-812.
APA	Yu, Dahua.,Yuan, Kai.,Zhao, Ling.,Zhao, Limei.,Dong, Minghao.,...&Tian, Jie.(2012).Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study.NMR IN BIOMEDICINE,25(5),806-812.
MLA	Yu, Dahua,et al."Regional homogeneity abnormalities in patients with interictal migraine without aura: a resting-state study".NMR IN BIOMEDICINE 25.5(2012):806-812.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
86.NMR in Biomedicin（175KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载