Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations | |
Hong, Qingqi1; Li, Qingde2; Wang, Beizhan1; Tian, Jie3; Xu, Fei1; Liu, Kunhong1; Cheng, Xuan1 | |
发表期刊 | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE |
ISSN | 0169-2607 |
2020-11-01 | |
卷号 | 196页码:13 |
通讯作者 | Liu, Kunhong(lkhqz@xmu.edu.cn) ; Cheng, Xuan(21408732@qq.com) |
摘要 | Background and Objective: High-quality vascular modeling is crucial for blood flow simulations, i.e., computational fluid dynamics (CFD). As without an accurate geometric representation of the smooth vascular surface, it is impossible to make meaningful blood flow simulations. The purpose of this work is to develop high-quality vascular modeling and modification method for blood flow computations. Methods: We develop a new technique for the accurate geometric modeling and modification of vasculatures using implicit extrusion surfaces (IES). In the proposed method, the skeleton of the vascular structure is subdivided into short curve segments, each of which is then represented implicitly locally as the intersection of two mutually orthogonal implicit surfaces defined by distance functions. A set of contour points is extracted and fitted with an implicit curve for accurately specifying the vessel cross-section profile, which is then extruded locally along the skeleton to fill the gaps between two vascular tube cross sections. We also present a new implicit geometric editing technique to modify the constructed vascular model with pathology for virtual stenting. Results: Experimental results and validations show that accurate vascular models with highly smooth surfaces can be generated by the proposed method. In addition, we conduct some blood flow simulations to indicate the effectiveness of proposed method for hemodynamic simulations. Conclusions: The proposed technique can achieve precise geometric models of vasculatures with any required degree of smoothness for reliable blood flow simulations. (C) 2020 Elsevier B.V. All rights reserved. |
关键词 | Geometric modeling Vascular visualization Implicit functions Blood flow simulation Extrusion surfaces |
DOI | 10.1016/j.cmpb.2020.105598 |
关键词[WOS] | VISUALIZATION ; SIMULATION ; RECONSTRUCTION ; SEGMENTATION ; ANGIOGRAPHY ; VALIDATION |
收录类别 | SCI |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China[61502402] ; National Natural Science Foundation of China[61,772,023] ; National Natural Science Foundation of China[61802322] ; Fundamental Research Funds for the Central Universities[20720180073] ; Fundamental Research Funds for the Central Universities[20720190003] ; National Key RD Program of China[2019QY1803] |
项目资助者 | National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; National Key RD Program of China |
WOS研究方向 | Computer Science ; Engineering ; Medical Informatics |
WOS类目 | Computer Science, Interdisciplinary Applications ; Computer Science, Theory & Methods ; Engineering, Biomedical ; Medical Informatics |
WOS记录号 | WOS:000580609200027 |
出版者 | ELSEVIER IRELAND LTD |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/41737 |
专题 | 中国科学院分子影像重点实验室 |
通讯作者 | Liu, Kunhong; Cheng, Xuan |
作者单位 | 1.Xiamen Univ, Sch Informat, Xiamen, Peoples R China 2.Univ Hull, Sch Engn & Comp Sci, Kingston Upon Hull, N Humberside, England 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Hong, Qingqi,Li, Qingde,Wang, Beizhan,et al. High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations[J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,2020,196:13. |
APA | Hong, Qingqi.,Li, Qingde.,Wang, Beizhan.,Tian, Jie.,Xu, Fei.,...&Cheng, Xuan.(2020).High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations.COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,196,13. |
MLA | Hong, Qingqi,et al."High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations".COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 196(2020):13. |
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