Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia

doi:10.1111/eip.13276

	Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia
	Li, Ling1,2 ; Rami, Fatima Zahra 1,2; Piao, Yan Hong 1,2; Lee, Bo Mi 1,2; Kim, Woo-Sung 1,2; Sui, Jing 3,4,5,6; Kim, Sung-Wan 7; Lee, Bong Ju 8; Kim, Jung Jin 9; Yu, Je-Chun 10; Lee, Kyu Young 11; Won, Seung-Hee 12; Lee, Seung-Hwan 13; Kim, Seung-Hyun 14; Kang, Shi Hyun 15; Kim, Euitae 16; Chung, Young Chul 1,2
发表期刊	EARLY INTERVENTION IN PSYCHIATRY
ISSN	1751-7885
	2022-02-06
页码	10
通讯作者	Chung, Young Chul(chungyc@jbnu.ac.kr)
摘要	Aim: Research on psychotic disorder not otherwise specified (PNOS) that clearly mentions its subgroups is very rare. This study was conducted to identify the demographic and clinical features, cognitive function, and 1-year outcomes of patients with early stage PNOS compared with those with early stage schizophrenia (SZ). Methods: The study subjects were 54 and 321 patients with PNOS and SZ, respectively, who were registered at least more than 1 year ago. Due to drop out, only 37 and 210 patients with PNOS and SZ were evaluated at the 1-year follow-up. We compared clinical variables (duration of untreated psychosis, symptom severity, self-rating scales, and so on), cognitive function, and short-term outcomes (treatment response, remission, compliance, drop out, relapse) between the two groups. Results: The patients with PNOS were associated with higher diagnostic stability (53.7%) compared with those in previous studies. They had lower symptom severity, better treatment response at 2 months and higher remission rates at 12 months, but poorer compliance at 6 months compared with patients with SZ. Level of cognitive impairment in PNOS was intermediate between those of SZ patients and healthy controls. Conclusions: These findings indicate that PNOS has unique clinical features, suggesting that it should be treated as a distinct clinical syndrome. At the same time, however, prevention of its possible progression to other psychotic disorders in some patients with PNOS is also important.
关键词	clinical staging diagnostic stability outcome psychotic disorder NOS
DOI	10.1111/eip.13276
关键词[WOS]	DIAGNOSTIC STABILITY ; DSM-IV ; PSYCHOMETRIC PROPERTIES ; 1ST EPISODE ; DEPRESSION ; RECOVERY ; VALIDITY ; SCALES ; BIRTH
收录类别	SCI
语种	英语
资助项目	Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea[HL19C0015] ; Korea Health Industry Development Institute[HI18C2383]
项目资助者	Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea ; Korea Health Industry Development Institute
WOS研究方向	Psychiatry
WOS类目	Psychiatry
WOS记录号	WOS:000751756700001
出版者	WILEY
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/47612
专题	脑图谱与类脑智能实验室_脑网络组研究
通讯作者	Chung, Young Chul
作者单位	1.Jeonbuk Natl Univ, Med Sch, Dept Psychiat, Jeonju 54907, South Korea 2.Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Biomed Res Inst, Res Inst Clin Med, Jeonju, South Korea 3.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Beijing, Peoples R China 7.Chonnam Natl Univ, Med Sch, Dept Psychiat, Gwangju, South Korea 8.Inje Univ, Haeundae Paik Hosp, Coll Med, Dept Psychiat, Busan, South Korea 9.Catholic Univ Korea, Seoul St Marys Hosp, Dept Psychiat, Seoul, South Korea 10.Eulji Univ, Eulji Univ Hosp, Sch Med, Dept Psychiat, Daejeon, South Korea 11.Eulji Univ, Eulji Gen Hosp, Sch Med, Dept Psychiat, Seoul, South Korea 12.Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea 13.Inje Univ, Coll Med, Dept Psychiat, Goyang, South Korea 14.Korea Univ, Coll Med, Guro Hosp, Dept Psychiat, Seoul, South Korea 15.Natl Ctr Mental Hlth, Dept Social Psychiat & Rehabil, Seoul, South Korea 16.Seoul Natl Univ, Bundang Hosp, Dept Psychiat, Seongnam, South Korea
推荐引用方式 GB/T 7714	Li, Ling,Rami, Fatima Zahra,Piao, Yan Hong,et al. Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia[J]. EARLY INTERVENTION IN PSYCHIATRY,2022:10.
APA	Li, Ling.,Rami, Fatima Zahra.,Piao, Yan Hong.,Lee, Bo Mi.,Kim, Woo-Sung.,...&Chung, Young Chul.(2022).Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia.EARLY INTERVENTION IN PSYCHIATRY,10.
MLA	Li, Ling,et al."Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia".EARLY INTERVENTION IN PSYCHIATRY (2022):10.