Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| Adaptive permissible region based random Kaczmarz reconstruction method for localization of carotid atherosclerotic plaques in fluorescence molecular tomography | |
Zhang, Peng1; Liu, Jie1 ; Yin, Lin2; An, Yu3,6; Zhang, Suhui4; Tong, Wei4; Hui, Hui2,5; Tian, Jie2,3,6,7
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| Source Publication | PHYSICS IN MEDICINE AND BIOLOGY
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| ISSN | 0031-9155 |
| 2022-09-07 | |
| Volume | 67Issue:17Pages:13 |
| Corresponding Author | Liu, Jie(jieliu@bjtu.edu.cn) ; Hui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org) |
| Abstract | Objective. In this study, we propose the adaptive permissible region based random Kaczmarz method as an improved reconstruction method to recover small carotid atherosclerotic plaque targets in rodents with high resolution in fluorescence molecular tomography (FMT). Approach. We introduce the random Kaczmarz method as an advanced minimization method to solve the FMT inverse problem. To satisfy the special condition of this method, we proposed an adaptive permissible region strategy based on traditional permissible region methods to flexibly compress the dimension of the solution space. Main results. Monte Carlo simulations, phantom experiments, and in vivo experiments demonstrate that the proposed method can recover the small carotid atherosclerotic plaque targets with high resolution and accuracy, and can achieve lower root mean squared error and distance error (DE) than other traditional methods. For targets with 1.5 mm diameter and 0.5 mm separation, the DE indicators can be improved by up to 40%. Moreover, the proposed method can be utilized for in vivo locating atherosclerotic plaques with high accuracy and robustness. Significance. We applied the random Kaczmarz method to solve the inverse problem in FMT and improve the reconstruction result via this advanced minimization method. We verified that the FMT technology has a great potential to locate and quantify atherosclerotic plaques with higher accuracy, and can be expanded to more preclinical research. |
| Keyword | fluorescence molecular tomography reconstruction method adaptive permissible region atherosclerotic plaques |
| DOI | 10.1088/1361-6560/ac8718 |
| WOS Keyword | MORPHOLOGICAL RECONSTRUCTION ; SPARSE RECONSTRUCTION ; IMAGE-RECONSTRUCTION ; OPTICAL TOMOGRAPHY ; ALGORITHM |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[KKA309004533] ; National Natural Science Foundation of China[81227901] ; National Natural Science Foundation of China[81671851] ; National Natural Science Foundation of China[81527805] ; National Natural Science Foundation of China[81571836] ; CAS Youth Innovation Promotion Association[2018167] ; CAS Key Technology Talent Program ; Project of High-Level Talents Team Introduction in Zhuhai City[Zhuhai HLHPTP201703] |
| Funding Organization | National Key Research and Development Program of China ; National Natural Science Foundation of China ; CAS Youth Innovation Promotion Association ; CAS Key Technology Talent Program ; Project of High-Level Talents Team Introduction in Zhuhai City |
| WOS Research Area | Engineering ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS Subject | Engineering, Biomedical ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS ID | WOS:000844321700001 |
| Publisher | IOP Publishing Ltd |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ia.ac.cn/handle/173211/50066 |
| Collection | 中国科学院分子影像重点实验室 |
| Corresponding Author | Liu, Jie; Hui, Hui; Tian, Jie |
| Affiliation | 1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China 2.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China 3.Beihang Univ, Sch Engn Med, Beijing 100191, Peoples R China 4.Peoples Liberat Army Gen Hosp, Med Ctr 6, Senior Dept Cardiol, Beijing 100853, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100080, Peoples R China 6.Beihang Univ, Minist Ind & Informat Technol, Key Lab Big Data Based Precis Med, Beijing 100191, Peoples R China 7.Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai 519000, Peoples R China |
| Corresponding Author Affilication | Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Peng,Liu, Jie,Yin, Lin,et al. Adaptive permissible region based random Kaczmarz reconstruction method for localization of carotid atherosclerotic plaques in fluorescence molecular tomography[J]. PHYSICS IN MEDICINE AND BIOLOGY,2022,67(17):13. |
| APA | Zhang, Peng.,Liu, Jie.,Yin, Lin.,An, Yu.,Zhang, Suhui.,...&Tian, Jie.(2022).Adaptive permissible region based random Kaczmarz reconstruction method for localization of carotid atherosclerotic plaques in fluorescence molecular tomography.PHYSICS IN MEDICINE AND BIOLOGY,67(17),13. |
| MLA | Zhang, Peng,et al."Adaptive permissible region based random Kaczmarz reconstruction method for localization of carotid atherosclerotic plaques in fluorescence molecular tomography".PHYSICS IN MEDICINE AND BIOLOGY 67.17(2022):13. |
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