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Neural indicator of positive reappraisal: A TMS-EEG study over the left VLPFC | |
Cao, Dan1,2; Qian, Zhenying3; Tang, Yingying3; Wang, Jijun3; Jiang, Tianzi2; Li, Yingjie1,4 | |
发表期刊 | Journal of Affective Disorders |
2022 | |
卷号 | 300页码:418-429 |
摘要 | BackgroundPositive reappraisal aims to reinterpret negative situations in a more positive light. Single-pulse transcranial magnetic stimulation (TMS) over the left ventrolateral prefrontal cortex (VLPFC) during positive reappraisal was suggested to improve emotion regulation capacity. However, it remains unclear whether the improvement of the capacity of emotion regulation was caused by the alterations of neural activity with TMS perturbation over the left VLPFC during positive reappraisal. MethodsSingle-pulse TMS was delivered among fifteen participants who engaged in positive reappraisal experiments with concurrent electroencephalogram (EEG) recordings. Participants repeated positive reappraisal experiments at three different stimulation settings: no stimulation, TMS pulses over the left VLPFC at 300 ms post-stimulus as the targeted stimulation and over the vertex as the control stimulation. ResultsTMS pulses over the left VLPFC at 300 ms post-stimuli increased late positive potential (LPP) amplitudes (300–800 ms) within the central-parietal and right prefrontal regions in response to the reappraisal stimuli compared with the negative stimuli. Moreover, changes in neural activity within the frontoparietal network contributed to the modulated LPP amplitudes of the reappraisal stimuli with the targeted stimulation. Importantly, the central-parietal LPP amplitudes of the reappraisal stimuli with the targeted stimulation was not only correlated with but also could predict the valence ratings using positive reappraisal. ConclusionOur study demonstrated a causal role of the left VLPFC in positive reappraisal, and provided a neural indicator to indicate the degree to which single-pulse TMS modulated the emotional experience using positive reappraisal. It shows promise to apply in future closed-loop neuromodulation. |
是否为代表性论文 | 是 |
七大方向——子方向分类 | 脑网络分析 |
国重实验室规划方向分类 | 认知机理与类脑学习 |
是否有论文关联数据集需要存交 | 否 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/51494 |
专题 | 脑图谱与类脑智能实验室_脑网络组研究 脑图谱与类脑智能实验室 |
通讯作者 | Jiang, Tianzi; Li, Yingjie |
作者单位 | 1.Institute of Biomedical Engineering, School of Life Science, Shanghai University, Shanghai 200444, China 2.Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100089, China 3.Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China 4.College of International education, Shanghai University, Shanghai 200444, China |
第一作者单位 | 模式识别国家重点实验室 |
通讯作者单位 | 模式识别国家重点实验室 |
推荐引用方式 GB/T 7714 | Cao, Dan,Qian, Zhenying,Tang, Yingying,et al. Neural indicator of positive reappraisal: A TMS-EEG study over the left VLPFC[J]. Journal of Affective Disorders,2022,300:418-429. |
APA | Cao, Dan,Qian, Zhenying,Tang, Yingying,Wang, Jijun,Jiang, Tianzi,&Li, Yingjie.(2022).Neural indicator of positive reappraisal: A TMS-EEG study over the left VLPFC.Journal of Affective Disorders,300,418-429. |
MLA | Cao, Dan,et al."Neural indicator of positive reappraisal: A TMS-EEG study over the left VLPFC".Journal of Affective Disorders 300(2022):418-429. |
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