Total variation regularization for bioluminescence tomography with an adaptive parameter choice approach

	Total variation regularization for bioluminescence tomography with an adaptive parameter choice approach
	Feng, Jinchao; Jia, Xiaowei; Jia, Kebin; Qin, Chenghu; Tian, Jie
	2011
会议名称	the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
会议录名称	Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS)
页码	3946-3949
会议日期	2011
会议地点	Cancun, Mexico
摘要	Abstract— In this paper, we explore the application of total variation regularization method for bioluminescence tomography (BLT) with an adaptive regularization parameter choice approach. Since BLT is a seriously ill-posed problem, therefore, l2 regularized methods are frequently adopted to recover the bioluminescent sources. However, l2 regularized methods typically lead to smooth reconstructions. In this paper, we investigated the use of total variation (TV) regularization to improve the quality of BLT reconstruction. Furthermore, the regularization parameter in TV method was chosen adaptively to make the proposed algorithm more stable. Results on simulation data provide evidence that the reconstructed source can be localized accurately compared with l2 method. Meanwhile, the effectiveness of utility of the parameter choice were illustrated. Finally, different levels of noisy data were added to validate the performance of the proposed algorithm.
关键词	Bioluminescence Adaptive Parameter
收录类别	EI
文献类型	会议论文
条目标识符	http://ir.ia.ac.cn/handle/173211/5448
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
推荐引用方式 GB/T 7714	Feng, Jinchao,Jia, Xiaowei,Jia, Kebin,et al. Total variation regularization for bioluminescence tomography with an adaptive parameter choice approach[C],2011:3946-3949.

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