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Evaluation of bilateral cingulum with tractography in patients with Alzheimer's disease
Xie, S; Xiao, JX; Wang, YH; Wu, HK; Gong, GL; Jiang, XX
Source PublicationNEUROREPORT
2005-08-22
Volume16Issue:12Pages:1275-1278
SubtypeArticle
AbstractA fiber-tracking algorithm was used to extract fractional anisotropy of bilateral cingulum bundles in patients with probable Alzheimer's disease and normal aging controls. In addition, their hippocampal volumes were measured manually. Relative to normal controls, Alzheimer's disease patients showed a significant reduction of fractional anisotropy and hippocampal volumes. Significant correlation was observed between fractional anisotropy values and volumes of hippocampi and mini-mental state examination scores. This study suggests that lower anisotropy of cingulum bundles is associated with cognitive dysfunction and atrophy of the limbic system.
KeywordAlzheimer's Disease Cingulum Bundle Diffusion Tensor Imaging
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordMILD COGNITIVE IMPAIRMENT ; VOXEL-BASED MORPHOMETRY ; GRAY-MATTER LOSS ; DIFFUSION TENSOR ; HIPPOCAMPAL VOLUME ; BRAIN ; AD
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectNeurosciences
WOS IDWOS:000231492600005
Citation statistics
Cited Times:58[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9059
Collection09年以前成果
Affiliation1.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China
3.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Xie, S,Xiao, JX,Wang, YH,et al. Evaluation of bilateral cingulum with tractography in patients with Alzheimer's disease[J]. NEUROREPORT,2005,16(12):1275-1278.
APA Xie, S,Xiao, JX,Wang, YH,Wu, HK,Gong, GL,&Jiang, XX.(2005).Evaluation of bilateral cingulum with tractography in patients with Alzheimer's disease.NEUROREPORT,16(12),1275-1278.
MLA Xie, S,et al."Evaluation of bilateral cingulum with tractography in patients with Alzheimer's disease".NEUROREPORT 16.12(2005):1275-1278.
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