CASIA OpenIR  > 09年以前成果
A multilevel adaptive finite element algorithm for bioluminescence tomography
Lv, Yujie; Tian, Jie; Cong, Wenxiang; Wang, Ge; Luo, Jie; Yang, Wei; Li, Hui
Source PublicationOPTICS EXPRESS
2006-09-04
Volume14Issue:18Pages:8211-8223
SubtypeArticle
AbstractAs a new mode of molecular imaging, bioluminescence tomography (BLT) has become a hot topic over the past two years. In this paper, a multilevel adaptive finite element algorithm is developed for BLT reconstruction. In this algorithm, the mesh is adaptively refined according to a posteriori error estimation, which helps not only to improve localization and quantification of sources but also to enhance the robustness and efficiency of reconstruction. In the numerical simulation, bioluminescent signals on the body surface of a heterogeneous phantom are synthesized in a molecular optical simulation environment (MOSE) that we developed to model the photon transportation via Monte Carlo simulation. The performance of the algorithm is evaluated in numerical tests involving single and multiple sources in various arrangements. The results demonstrate the merits and potential of the multilevel adaptive approach for BLT. (c) 2006 Optical Society of America.
KeywordTomography Image Reconstruction Techniques Spectroscopy Luminescence Fluorescence
WOS HeadingsScience & Technology ; Physical Sciences
WOS KeywordGENE-EXPRESSION ; LIGHT ; RECONSTRUCTION ; TRANSPORT ; TISSUE ; SYSTEM ; MEDIA
Indexed BySCI
Language英语
WOS Research AreaOptics
WOS SubjectOptics
WOS IDWOS:000240460100025
Citation statistics
Cited Times:134[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9329
Collection09年以前成果
Corresponding AuthorTian, Jie
Affiliation1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China
2.Univ Iowa, Dept Radiol, Bioluminescence Tomog Lab, Iowa City, IA 52242 USA
3.Xidian Univ, Life Sci Ctr, Xian 710071, Peoples R China
Recommended Citation
GB/T 7714
Lv, Yujie,Tian, Jie,Cong, Wenxiang,et al. A multilevel adaptive finite element algorithm for bioluminescence tomography[J]. OPTICS EXPRESS,2006,14(18):8211-8223.
APA Lv, Yujie.,Tian, Jie.,Cong, Wenxiang.,Wang, Ge.,Luo, Jie.,...&Li, Hui.(2006).A multilevel adaptive finite element algorithm for bioluminescence tomography.OPTICS EXPRESS,14(18),8211-8223.
MLA Lv, Yujie,et al."A multilevel adaptive finite element algorithm for bioluminescence tomography".OPTICS EXPRESS 14.18(2006):8211-8223.
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