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A multilevel adaptive finite element algorithm for bioluminescence tomography | |
Lv, Yujie; Tian, Jie; Cong, Wenxiang; Wang, Ge; Luo, Jie; Yang, Wei; Li, Hui | |
发表期刊 | OPTICS EXPRESS |
2006-09-04 | |
卷号 | 14期号:18页码:8211-8223 |
文章类型 | Article |
摘要 | As a new mode of molecular imaging, bioluminescence tomography (BLT) has become a hot topic over the past two years. In this paper, a multilevel adaptive finite element algorithm is developed for BLT reconstruction. In this algorithm, the mesh is adaptively refined according to a posteriori error estimation, which helps not only to improve localization and quantification of sources but also to enhance the robustness and efficiency of reconstruction. In the numerical simulation, bioluminescent signals on the body surface of a heterogeneous phantom are synthesized in a molecular optical simulation environment (MOSE) that we developed to model the photon transportation via Monte Carlo simulation. The performance of the algorithm is evaluated in numerical tests involving single and multiple sources in various arrangements. The results demonstrate the merits and potential of the multilevel adaptive approach for BLT. (c) 2006 Optical Society of America. |
关键词 | Tomography Image Reconstruction Techniques Spectroscopy Luminescence Fluorescence |
WOS标题词 | Science & Technology ; Physical Sciences |
关键词[WOS] | GENE-EXPRESSION ; LIGHT ; RECONSTRUCTION ; TRANSPORT ; TISSUE ; SYSTEM ; MEDIA |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Optics |
WOS类目 | Optics |
WOS记录号 | WOS:000240460100025 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/9329 |
专题 | 09年以前成果 |
通讯作者 | Tian, Jie |
作者单位 | 1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China 2.Univ Iowa, Dept Radiol, Bioluminescence Tomog Lab, Iowa City, IA 52242 USA 3.Xidian Univ, Life Sci Ctr, Xian 710071, Peoples R China |
推荐引用方式 GB/T 7714 | Lv, Yujie,Tian, Jie,Cong, Wenxiang,et al. A multilevel adaptive finite element algorithm for bioluminescence tomography[J]. OPTICS EXPRESS,2006,14(18):8211-8223. |
APA | Lv, Yujie.,Tian, Jie.,Cong, Wenxiang.,Wang, Ge.,Luo, Jie.,...&Li, Hui.(2006).A multilevel adaptive finite element algorithm for bioluminescence tomography.OPTICS EXPRESS,14(18),8211-8223. |
MLA | Lv, Yujie,et al."A multilevel adaptive finite element algorithm for bioluminescence tomography".OPTICS EXPRESS 14.18(2006):8211-8223. |
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