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A multilevel adaptive finite element algorithm for bioluminescence tomography
Lv, Yujie; Tian, Jie; Cong, Wenxiang; Wang, Ge; Luo, Jie; Yang, Wei; Li, Hui
2006-09-04
发表期刊OPTICS EXPRESS
卷号14期号:18页码:8211-8223
文章类型Article
摘要As a new mode of molecular imaging, bioluminescence tomography (BLT) has become a hot topic over the past two years. In this paper, a multilevel adaptive finite element algorithm is developed for BLT reconstruction. In this algorithm, the mesh is adaptively refined according to a posteriori error estimation, which helps not only to improve localization and quantification of sources but also to enhance the robustness and efficiency of reconstruction. In the numerical simulation, bioluminescent signals on the body surface of a heterogeneous phantom are synthesized in a molecular optical simulation environment (MOSE) that we developed to model the photon transportation via Monte Carlo simulation. The performance of the algorithm is evaluated in numerical tests involving single and multiple sources in various arrangements. The results demonstrate the merits and potential of the multilevel adaptive approach for BLT. (c) 2006 Optical Society of America.
关键词Tomography Image Reconstruction Techniques Spectroscopy Luminescence Fluorescence
WOS标题词Science & Technology ; Physical Sciences
关键词[WOS]GENE-EXPRESSION ; LIGHT ; RECONSTRUCTION ; TRANSPORT ; TISSUE ; SYSTEM ; MEDIA
收录类别SCI
语种英语
WOS研究方向Optics
WOS类目Optics
WOS记录号WOS:000240460100025
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9329
专题09年以前成果
通讯作者Tian, Jie
作者单位1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100080, Peoples R China
2.Univ Iowa, Dept Radiol, Bioluminescence Tomog Lab, Iowa City, IA 52242 USA
3.Xidian Univ, Life Sci Ctr, Xian 710071, Peoples R China
推荐引用方式
GB/T 7714
Lv, Yujie,Tian, Jie,Cong, Wenxiang,et al. A multilevel adaptive finite element algorithm for bioluminescence tomography[J]. OPTICS EXPRESS,2006,14(18):8211-8223.
APA Lv, Yujie.,Tian, Jie.,Cong, Wenxiang.,Wang, Ge.,Luo, Jie.,...&Li, Hui.(2006).A multilevel adaptive finite element algorithm for bioluminescence tomography.OPTICS EXPRESS,14(18),8211-8223.
MLA Lv, Yujie,et al."A multilevel adaptive finite element algorithm for bioluminescence tomography".OPTICS EXPRESS 14.18(2006):8211-8223.
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