CASIA OpenIR  > 09年以前成果
White matter integrity of the whole brain is disrupted in first-episode schizophrenia
Hao, YH; Liu, ZN; Jiang, TZ; Gong, GL; Liu, HH; Tan, LH; Kuang, F; Xu, L; Yi, YH; Zhang, ZS
Source PublicationNEUROREPORT
2006-01-23
Volume17Issue:1Pages:23-26
SubtypeArticle
AbstractDiffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral pecluncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulum bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia.
KeywordDiffusion Tensor Imaging First-episode Schizophrenia Fractional Anisotropy White Matter
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordDIFFUSION ANISOTROPY ; ANTERIOR CINGULUM ; CORPUS-CALLOSUM ; WORKING-MEMORY ; ABNORMALITIES ; MRI ; CORTEX
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectNeurosciences
WOS IDWOS:000234527700006
Citation statistics
Cited Times:110[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9383
Collection09年以前成果
Affiliation1.Cent S Univ, Inst Mental Hlth, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China
3.Chinese Acad Sci, Lab Learning & Memory, Kunming Inst Zool, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Hao, YH,Liu, ZN,Jiang, TZ,et al. White matter integrity of the whole brain is disrupted in first-episode schizophrenia[J]. NEUROREPORT,2006,17(1):23-26.
APA Hao, YH.,Liu, ZN.,Jiang, TZ.,Gong, GL.,Liu, HH.,...&Zhang, ZS.(2006).White matter integrity of the whole brain is disrupted in first-episode schizophrenia.NEUROREPORT,17(1),23-26.
MLA Hao, YH,et al."White matter integrity of the whole brain is disrupted in first-episode schizophrenia".NEUROREPORT 17.1(2006):23-26.
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