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White matter integrity of the whole brain is disrupted in first-episode schizophrenia
Hao, YH; Liu, ZN; Jiang, TZ; Gong, GL; Liu, HH; Tan, LH; Kuang, F; Xu, L; Yi, YH; Zhang, ZS
2006-01-23
发表期刊NEUROREPORT
卷号17期号:1页码:23-26
文章类型Article
摘要Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral pecluncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulum bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia.
关键词Diffusion Tensor Imaging First-episode Schizophrenia Fractional Anisotropy White Matter
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]DIFFUSION ANISOTROPY ; ANTERIOR CINGULUM ; CORPUS-CALLOSUM ; WORKING-MEMORY ; ABNORMALITIES ; MRI ; CORTEX
收录类别SCI
语种英语
WOS研究方向Neurosciences & Neurology
WOS类目Neurosciences
WOS记录号WOS:000234527700006
引用统计
被引频次:107[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9383
专题09年以前成果
作者单位1.Cent S Univ, Inst Mental Hlth, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China
3.Chinese Acad Sci, Lab Learning & Memory, Kunming Inst Zool, Yunnan, Peoples R China
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GB/T 7714
Hao, YH,Liu, ZN,Jiang, TZ,et al. White matter integrity of the whole brain is disrupted in first-episode schizophrenia[J]. NEUROREPORT,2006,17(1):23-26.
APA Hao, YH.,Liu, ZN.,Jiang, TZ.,Gong, GL.,Liu, HH.,...&Zhang, ZS.(2006).White matter integrity of the whole brain is disrupted in first-episode schizophrenia.NEUROREPORT,17(1),23-26.
MLA Hao, YH,et al."White matter integrity of the whole brain is disrupted in first-episode schizophrenia".NEUROREPORT 17.1(2006):23-26.
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