Finer discrimination of brain activation with local multivariate distance

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	Finer discrimination of brain activation with local multivariate distance
	Zhen Zonglei; Tian Jie; Zhang Hui; Tian, Jie
发表期刊	PROGRESS IN NATURAL SCIENCE
	2007-12-01
卷号	17 期号:12 页码:1508-1514
文章类型	Article
摘要	The organization of human brain function is diverse on different spatial scales. Various cognitive states are always represented as distinct activity patterns across the specific brain region on fine scales. Conventional univariate analysis of functional MRI data seeks to determine how a particular cognitive state is encoded in brain activity by analyzing each voxel separately without considering the fine-scale patterns information contained in the local brain regions. In this paper, a local multivariate distance mapping (LMDM) technique is proposed to detect the brain activation and to map the fine-scale brain activity patterns. LMDM directly represents the local brain activity with the patterns across multiple voxels rather than individual voxels, and it employs the multivariate distance between different patterns to discriminate the brain state on fine scales. Experiments with simulated and real fMRI data demonstrate that LMDM technique can dramatically increase the sensitivity of the detection for the fine-scale brain activity patterns which contain the subtle information of the experimental conditions.
关键词	Functional Magnetic Resonance Imaging (Fmri) Statistical Analysis Multivariate Distance Local Pattern Pattern Classification
WOS标题词	Science & Technology ; Technology
关键词[WOS]	FALSE DISCOVERY RATE ; FUSIFORM FACE AREA ; FUNCTIONAL MRI ; FMRI ; REPRESENTATIONS ; PERCEPTION ; OBJECTS ; CORTEX
收录类别	SCI
语种	英语
WOS研究方向	Materials Science ; Science & Technology - Other Topics
WOS类目	Materials Science, Multidisciplinary ; Multidisciplinary Sciences
WOS记录号	WOS:000253164300016
引用统计
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/9390
专题	09年以前成果
通讯作者	Tian, Jie
作者单位	Chinese Acad Sci, Inst Automat, Key Lab Complex Syst & Intelligence Sci, Med Image Proc Grp, Beijing 100080, Peoples R China
第一作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Zhen Zonglei,Tian Jie,Zhang Hui,et al. Finer discrimination of brain activation with local multivariate distance[J]. PROGRESS IN NATURAL SCIENCE,2007,17(12):1508-1514.
APA	Zhen Zonglei,Tian Jie,Zhang Hui,&Tian, Jie.(2007).Finer discrimination of brain activation with local multivariate distance.PROGRESS IN NATURAL SCIENCE,17(12),1508-1514.
MLA	Zhen Zonglei,et al."Finer discrimination of brain activation with local multivariate distance".PROGRESS IN NATURAL SCIENCE 17.12(2007):1508-1514.

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