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Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies
Liu, Yong1; Wang, Kun1; Yu, Chunshui2; He, Yong1,3; Zhou, Yuan1; Liang, Meng1,4; Wang, Liang2; Jiang, Tianzi1; Jiang Tianzi
2008
发表期刊NEUROPSYCHOLOGIA
卷号46期号:6页码:1648-1656
文章类型Review
摘要Resting-state functional magnetic resonance imaging (fMRI), a promising technique for measuring brain activities during rest, has attracted much attention in the past few years. In this paper, we review recent progress on the study of Alzheimer's disease (AD) based on resting-state fMRI. First, we briefly introduce some AD-related studies from other groups. Then we describe our AD-related work in detail from three aspects: (1) alterations in regional homogeneity (ReHo) of the fMRI signal in the resting state, (2) altered patterns of functional connectivity from regions of interest and whole brain analyses, and (3) discriminative analyses based on classification features from resting-state fMRI data for differentiating AD patients from healthy elders. Finally, we summarize the main results and some prospects for future work. (c) 2008 Published by Elsevier Ltd.
关键词Alzheimer's Disease Resting-state Fmri Reho Functional Connectivity Biomarkers
WOS标题词Science & Technology ; Social Sciences ; Life Sciences & Biomedicine
关键词[WOS]MILD COGNITIVE IMPAIRMENT ; INDEPENDENT COMPONENT ANALYSIS ; POSITRON-EMISSION-TOMOGRAPHY ; MAGNETIC-RESONANCE ; BRAIN ACTIVITY ; DEFAULT-MODE ; FDG-PET ; DISCONNECTION SYNDROME ; CINGULATE CORTEX ; NETWORK ANALYSIS
收录类别SCI ; SSCi
语种英语
WOS研究方向Behavioral Sciences ; Neurosciences & Neurology ; Psychology
WOS类目Behavioral Sciences ; Neurosciences ; Psychology, Experimental
WOS记录号WOS:000257128200007
引用统计
被引频次:137[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9609
专题09年以前成果
通讯作者Jiang Tianzi
作者单位1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China
2.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China
3.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ H3A 2B4, Canada
4.Univ Oxford, Dept Physiol Anat & Genet, Oxford OX1 3QX, England
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GB/T 7714
Liu, Yong,Wang, Kun,Yu, Chunshui,et al. Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies[J]. NEUROPSYCHOLOGIA,2008,46(6):1648-1656.
APA Liu, Yong.,Wang, Kun.,Yu, Chunshui.,He, Yong.,Zhou, Yuan.,...&Jiang Tianzi.(2008).Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies.NEUROPSYCHOLOGIA,46(6),1648-1656.
MLA Liu, Yong,et al."Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies".NEUROPSYCHOLOGIA 46.6(2008):1648-1656.
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