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Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies
Liu, Yong1; Wang, Kun1; Yu, Chunshui2; He, Yong1,3; Zhou, Yuan1; Liang, Meng1,4; Wang, Liang2; Jiang, Tianzi1; Jiang Tianzi
Source PublicationNEUROPSYCHOLOGIA
2008
Volume46Issue:6Pages:1648-1656
SubtypeReview
AbstractResting-state functional magnetic resonance imaging (fMRI), a promising technique for measuring brain activities during rest, has attracted much attention in the past few years. In this paper, we review recent progress on the study of Alzheimer's disease (AD) based on resting-state fMRI. First, we briefly introduce some AD-related studies from other groups. Then we describe our AD-related work in detail from three aspects: (1) alterations in regional homogeneity (ReHo) of the fMRI signal in the resting state, (2) altered patterns of functional connectivity from regions of interest and whole brain analyses, and (3) discriminative analyses based on classification features from resting-state fMRI data for differentiating AD patients from healthy elders. Finally, we summarize the main results and some prospects for future work. (c) 2008 Published by Elsevier Ltd.
KeywordAlzheimer's Disease Resting-state Fmri Reho Functional Connectivity Biomarkers
WOS HeadingsScience & Technology ; Social Sciences ; Life Sciences & Biomedicine
WOS KeywordMILD COGNITIVE IMPAIRMENT ; INDEPENDENT COMPONENT ANALYSIS ; POSITRON-EMISSION-TOMOGRAPHY ; MAGNETIC-RESONANCE ; BRAIN ACTIVITY ; DEFAULT-MODE ; FDG-PET ; DISCONNECTION SYNDROME ; CINGULATE CORTEX ; NETWORK ANALYSIS
Indexed BySCI ; SSCi
Language英语
WOS Research AreaBehavioral Sciences ; Neurosciences & Neurology ; Psychology
WOS SubjectBehavioral Sciences ; Neurosciences ; Psychology, Experimental
WOS IDWOS:000257128200007
Citation statistics
Cited Times:142[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9609
Collection09年以前成果
Corresponding AuthorJiang Tianzi
Affiliation1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China
2.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China
3.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ H3A 2B4, Canada
4.Univ Oxford, Dept Physiol Anat & Genet, Oxford OX1 3QX, England
Recommended Citation
GB/T 7714
Liu, Yong,Wang, Kun,Yu, Chunshui,et al. Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies[J]. NEUROPSYCHOLOGIA,2008,46(6):1648-1656.
APA Liu, Yong.,Wang, Kun.,Yu, Chunshui.,He, Yong.,Zhou, Yuan.,...&Jiang Tianzi.(2008).Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies.NEUROPSYCHOLOGIA,46(6),1648-1656.
MLA Liu, Yong,et al."Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies".NEUROPSYCHOLOGIA 46.6(2008):1648-1656.
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