CASIA OpenIR  > 09年以前成果
Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder
Zhu, Chao-Zhe1,2; Zang, Yu-Feng1,2; Cao, Qing-Jiu3; Yan, Chao-Gan1; He, Yong4; Jiang, Tian-Zi2; Sui, Man-Qiu3; Wang, Yu-Feng3
Source PublicationNEUROIMAGE
2008-03-01
Volume40Issue:1Pages:110-120
SubtypeArticle
AbstractIn this study a resting-state fMRI based classifier, for the first time, was proposed and applied to discriminate children with attention-deficit/hyperactivity disorder (ADHD) from normal controls. On the basis of regional homogeneity (ReHo), a mapping of brain function at resting state, PCA-based Fisher discriminative analysis (PC-FDA) was trained to build a linear classifier. Permutation test was then conducted to identify the brain areas with the most significant contribution to the final discrimination. Experimental results showed a correct classification rate of 85% using a leave-one-out cross-validation. Moreover, some highly discriminative brain regions, like the prefrontal cortex and anterior cingulate cortex, well confirmed the previous findings on ADHD. Interestingly, some important but less reported regions such as the thalamus were also identified. We conclude that the classifier, using resting-state brain function as classification feature, has potential ability to improve current diagnosis and treatment evaluation of ADHD. (c) 2007 Published by Elsevier Inc.
KeywordFisher Discriminative Analysis Adhd Reho Resting State Fmri
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordDEFICIT HYPERACTIVITY DISORDER ; ANTERIOR CINGULATE CORTEX ; REGIONAL HOMOGENEITY ; PERFORMANCE METRICS ; ACTIVATION PATTERNS ; ALZHEIMERS-DISEASE ; CONNECTIVITY ; MRI ; CLASSIFICATION ; CHILDREN
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectNeurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000253362100012
Citation statistics
Cited Times:149[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9654
Collection09年以前成果
Affiliation1.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100875, Peoples R China
3.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
4.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging, Montreal, PQ H3A 2B4, Canada
Recommended Citation
GB/T 7714
Zhu, Chao-Zhe,Zang, Yu-Feng,Cao, Qing-Jiu,et al. Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder[J]. NEUROIMAGE,2008,40(1):110-120.
APA Zhu, Chao-Zhe.,Zang, Yu-Feng.,Cao, Qing-Jiu.,Yan, Chao-Gan.,He, Yong.,...&Wang, Yu-Feng.(2008).Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder.NEUROIMAGE,40(1),110-120.
MLA Zhu, Chao-Zhe,et al."Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder".NEUROIMAGE 40.1(2008):110-120.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhu, Chao-Zhe]'s Articles
[Zang, Yu-Feng]'s Articles
[Cao, Qing-Jiu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhu, Chao-Zhe]'s Articles
[Zang, Yu-Feng]'s Articles
[Cao, Qing-Jiu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhu, Chao-Zhe]'s Articles
[Zang, Yu-Feng]'s Articles
[Cao, Qing-Jiu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.