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Systematic benchmarking of microarray data feature extraction and classification
Zrang, Jing; Jiang, Tianzi; Liu, Bing; Jiang, Xingpeng; Zhao, Huizhi
2008-05-01
发表期刊INTERNATIONAL JOURNAL OF COMPUTER MATHEMATICS
卷号85期号:5页码:803-811
文章类型Article
摘要A combination of microarrays with classification methods is a promising approach to supporting clinical management decisions in oncology. The aim of this paper is to systematically benchmark the role of classification models. Each classification model is a combination of one feature extraction method and one classification method. We consider four feature extraction methods and five classification methods, from which 20 classification models can be derived. The feature extraction methods are t-statistics, non-parametric Wilcoxon statistics, ad hoc signal-to-noise statistics, and principal component analysis (PCA), and the classification methods are Fisher linear discriminant analysis (FLDA), the support vector machine (SVM), the k nearest-neighbour classifier (kNN), diagonal linear discriminant analysis (DLDA), and diagonal quadratic discriminant analysis (DQDA). Twenty randomizations of each of three binary cancer classification problems derived from publicly available datasets are examined. PCA plus FLDA is found to be the optimal classification model.
关键词Pca T-statistics Flda Nearest-neighbour Classifier Leave-one-out Cross-validation
WOS标题词Science & Technology ; Physical Sciences
关键词[WOS]DIFFERENTIALLY EXPRESSED GENES ; CANCER ; LDA
收录类别SCI
语种英语
WOS研究方向Mathematics
WOS类目Mathematics, Applied
WOS记录号WOS:000255869700009
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9694
专题09年以前成果
作者单位Chinese Acad Sci, LIAMA, Sino French Lab Comp Sci Automat & Appl Math, Inst Automat, Beijing 100080, Peoples R China
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GB/T 7714
Zrang, Jing,Jiang, Tianzi,Liu, Bing,et al. Systematic benchmarking of microarray data feature extraction and classification[J]. INTERNATIONAL JOURNAL OF COMPUTER MATHEMATICS,2008,85(5):803-811.
APA Zrang, Jing,Jiang, Tianzi,Liu, Bing,Jiang, Xingpeng,&Zhao, Huizhi.(2008).Systematic benchmarking of microarray data feature extraction and classification.INTERNATIONAL JOURNAL OF COMPUTER MATHEMATICS,85(5),803-811.
MLA Zrang, Jing,et al."Systematic benchmarking of microarray data feature extraction and classification".INTERNATIONAL JOURNAL OF COMPUTER MATHEMATICS 85.5(2008):803-811.
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