CASIA OpenIR  > 09年以前成果
Enhanced resting-state brain activities in ADHD patients: A fMRI study
Tian, Lixia2; Jiang, Tianzi1; Liang, Meng1; Zang, Yufeng1; He, Yong1; Sui, Manqiu3; Wang, Yufeng3
Source PublicationBRAIN & DEVELOPMENT
2008-05-01
Volume30Issue:5Pages:342-348
SubtypeArticle
AbstractResting-state functional MRI (fMRI) could be an advantageous choice for clinical applications by virtue of its clinical convenience and non-invasiveness. Without explicit stimulus, resting-state brain activity patterns cannot be obtained using any model-driven method. In this study, we advanced a measure named resting-state activity index (RSAI) to evaluate the resting-state brain activities. Using RSAI, we first investigated the resting-state brain activity patterns in normal adolescents to test the validity of this RSAI measure. Then we compared the resting-state brain activity patterns of Attention deficit hyperactivity disorder (ADHD) patients to those of their matched controls. According to the resultant brain activity patterns, we suggest that RSAI could be an applicable measure to evaluate resting-state brain activities. As compared to the controls, the ADHD patients exhibited more significant resting-state activities in basic sensory and sensory-related cortices. This finding was in accordance with ADHD symptoms of inattention. (c) 2007 Elsevier B.V. All rights reserved.
KeywordRegional Homogeneity Low-frequency Fluctuations Resting-state Activity Index (Rsai) Sensory
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordDEFICIT HYPERACTIVITY DISORDER ; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER ; ANTERIOR CINGULATE CORTEX ; FUNCTIONAL CONNECTIVITY ; DEFAULT MODE ; CEREBRAL-CORTEX ; BLOOD-FLOW ; CHILDREN ; FLUCTUATIONS ; MRI
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectClinical Neurology
WOS IDWOS:000255526800006
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9695
Collection09年以前成果
Affiliation1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
2.Beijing Jiaotong Univ, Dept Biomed Engn, Sch Comp & Informat Technol, Beijing 100044, Peoples R China
3.Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Tian, Lixia,Jiang, Tianzi,Liang, Meng,et al. Enhanced resting-state brain activities in ADHD patients: A fMRI study[J]. BRAIN & DEVELOPMENT,2008,30(5):342-348.
APA Tian, Lixia.,Jiang, Tianzi.,Liang, Meng.,Zang, Yufeng.,He, Yong.,...&Wang, Yufeng.(2008).Enhanced resting-state brain activities in ADHD patients: A fMRI study.BRAIN & DEVELOPMENT,30(5),342-348.
MLA Tian, Lixia,et al."Enhanced resting-state brain activities in ADHD patients: A fMRI study".BRAIN & DEVELOPMENT 30.5(2008):342-348.
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