Dynamic Characteristic Analysis of HIV Mother to Child Transmission in China
Wang, Jun-Jie1; Reilly, Kathleen Heather1,2; Han, Hua3; Peng, Zhi-Hang4; Wang, Ning1
2010-10-01
发表期刊BIOMEDICAL AND ENVIRONMENTAL SCIENCES
卷号23期号:5页码:402-408
文章类型Article
摘要Objective to explore dynamic characteristics of the HIV mother to child transmission (MTCT) epidemic in China. Methods A deterministic dynamic transmission model was used to determine the effect of key parameters on the likely long-term trends of the HIV MTCT epidemic in China. Matlab 7.0 was used to develop the model. Results The number of the susceptibles (S), the transmission rate (beta), and the screening proportion (alpha) of HIV positive pregnant women have the greatest impact on the HIV MTCT epidemic in China. The growth of the MTCT epidemic in China could not be controlled only by decreasing the MTCT transmission rate. The prevalence of HIV positive women should be reduced and more pregnant women should be tested for HIV. Conclusion Prevention of MTCT (PMTCT) should focus not only on the reduction of HIV transmission rates and incidences of HIV among women but also on the increase of HIV testing for pregnant women. The most cost-effective PMTCT means for China should be investigated in future studies.
关键词Mother To Child Transmission Dynamic Model Hiv China
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]IMMUNODEFICIENCY-VIRUS TYPE-1 ; ACTIVE ANTIRETROVIRAL THERAPY ; PREGNANT-WOMEN ; INFECTION ; PREVENTION ; SURVIVAL ; HIV/AIDS ; INFANTS ; PREVALENCE ; MODEL
收录类别SCI
语种英语
WOS研究方向Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
WOS类目Environmental Sciences ; Public, Environmental & Occupational Health
WOS记录号WOS:000284393500010
引用统计
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9724
专题国家专用集成电路设计工程技术研究中心
作者单位1.China Ctr Dis Control & Prevent, Natl Ctr AIDS STD Control & Prevent, Beijing 100050, Peoples R China
2.Tulane Univ, Sch Publ Hlth & Trop Med, Hlth Sci Ctr, New Orleans, LA USA
3.Chinese Acad Sci, Inst Automat, Natl ASIC Design Engn Ctr, Beijing 100190, Peoples R China
4.Nanjing Med Univ, Dept Epidemiol & Biostat, Nanjing 210029, Peoples R China
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Wang, Jun-Jie,Reilly, Kathleen Heather,Han, Hua,et al. Dynamic Characteristic Analysis of HIV Mother to Child Transmission in China[J]. BIOMEDICAL AND ENVIRONMENTAL SCIENCES,2010,23(5):402-408.
APA Wang, Jun-Jie,Reilly, Kathleen Heather,Han, Hua,Peng, Zhi-Hang,&Wang, Ning.(2010).Dynamic Characteristic Analysis of HIV Mother to Child Transmission in China.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,23(5),402-408.
MLA Wang, Jun-Jie,et al."Dynamic Characteristic Analysis of HIV Mother to Child Transmission in China".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 23.5(2010):402-408.
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